Y Combinator S26 Batch Companies
Y Combinator S26 Companies
Startup Batches
Welcome to our interactive overview of Y Combinator's S26 batch. Below, you'll find a sortable, filterable table showcasing portfolio companies from this cohort.
Each row details:
- Company name and sector (spanning B2B SaaS, Healthcare, Fintech, Biotech, Construction, Analytics, Consumer, Deep Tech, and more)
- Funding stage to help you gauge maturity and runway
- YC Partner assignment for insight into mentorship and domain expertise
Use this table to:
- Explore Y Combinator's current investment focus, spotting which industries and technologies are gaining traction
- Identify promising directions by filtering sectors or funding stages for your own market research or strategic planning
- Quickly find founder contacts for networking, partnership, or investment outreach
Dive in now to track updates in real time, uncover market trends, potential collaborators, and the next wave of disruptive startups — all in one centralized view.
- Company Website
- tsenta.com
- One-Liner
- AI job application agent for seekers
- HQ Country
- United States
- Company Website
- archal.ai
- One-Liner
- Eval platform for autonomous software
- HQ Country
- United States
- Company Website
- controlseat.com
- One-Liner
- AI-native layer for SCADA systems
- HQ Country
- United States
- Company Website
- guildai.co
- One-Liner
- AI-native defense supply chain layer
- HQ Country
- United States
- Company Website
- codag.ai
- One-Liner
- Log compression for AI incident agents
- HQ Country
- United States
- Company Website
- rex.inc
- One-Liner
- AI order-to-cash workforce for enterprises
- HQ Country
- United Kingdom
- Company Website
- context.dev
- One-Liner
- Structured web data for AI agents
- HQ Country
- United States
- Company Website
- realpact.ai
- One-Liner
- AI agents for real estate contracts
- HQ Country
- United States
- Company Website
- caregp.com.au
- One-Liner
- AI-native agent suite for GP clinics in Australia
- HQ Country
- Australia
- Company Website
- agentcard.sh
- One-Liner
- AI agent debit cards for single-use payments
- HQ Country
- United States
- Company Website
- cerenovus.ai
- One-Liner
- AI company brain for company knowledge
- Product Description
- Cerenovus aggregates company files, emails, Slack messages, spreadsheets, and meeting notes into a single markdown knowledge graph. The Y C…
- Company Website
- machine0.io
- One-Liner
- Backed by Y Combinator for persistent AI VMs
- HQ Country
- United States
- Company Website
- getprescience.com
- One-Liner
- Health benefits platform for ambitious employers
- HQ Country
- United States
- Company Website
- hop-aero.com
- One-Liner
- Building a physical internet for aviation infrastructure
- HQ Country
- United States
- Company Website
- tryglen.com
- One-Liner
- Shared memory layer for AI agents
- HQ Country
- United States
- Company Website
- touchmark.ai
- One-Liner
- Quality-based pricing for AI outputs
- HQ Country
- United Kingdom
- Company Website
- mireye.com
- One-Liner
- Federal-grade geospatial ground truth for AI
- HQ Country
- United States
- Company Website
- pango.ai
- One-Liner
- Agentic OS for e-commerce logistics
- Product Description
- Pango is an Agentic OS for e-commerce operations that automates delivery, tracking, returns, transport, and customer support. The company d…
- Company Website
- levocred.com
- One-Liner
- AI operating system for structured credit
- HQ Country
- United States
- Company Website
- usetruffle.ai
- One-Liner
- AI-native back office for restaurants
- Product Description
- Truffle is an AI-native operating system for hospitality that the site describes as the autonomous back of house for restaurants. It combin…
- Company Website
- osmaura.com
- One-Liner
- Business development brain for law firms
- HQ Country
- United States
- Company Website
- latolabs.io
- One-Liner
- Agent-native research for investors
- HQ Country
- United Kingdom
- Company Website
- bloomylearning.com
- One-Liner
- AI-powered K-12 mastery learning
- Product Description
- Bloomy is an AI-powered, competency-based learning platform for K-12 students. It combines personalized learning journeys, Socratic tutorin…
- Company Website
- useblueprints.ai
- One-Liner
- Autonomous prediction-market trading agents
- Employee Count
- 1-10
- Company Website
- askshepherd.ai
- One-Liner
- AI work memory for team tools
- HQ Country
- United States
- Company Website
- markovstudios.com
- One-Liner
- Harvests high-quality training data for robotics
- Employee Count
- 1-10
- Company Website
- talentpluto.com
- One-Liner
- Warm introductions for elite GTM talent in NYC & SF startups
- Employee Count
- 1-10
- Company Website
- insurf.io
- One-Liner
- AI-native health insurance decision graph
- Employee Count
- 1-10
- Company Website
- parasma.com
- One-Liner
- Biological compute using living neurons
- Employee Count
- 1-10
- Company Website
- atlasdiscovery.bio
- One-Liner
- Predictive drug-response models for biotech
- Product Description
- Atlas Discovery builds foundation models of patient drug response using pre-clinical and clinical data. Its research describes predicting t…
- Company Website
- florin.inc
- One-Liner
- Startup banking with FDIC-protected accounts
- HQ Country
- United States
- Company Website
- flowmanual.com
- One-Liner
- Document intelligence for MEP contractors
- Product Description
- FlowManual reads contract, specification, bid, and invoice documents for HVAC and MEP contractors. It flags scope items, price references, …
- Company Website
- pothlabs.com
- One-Liner
- Truth-seeking AI for customer feedback
- Product Description
- Poth Labs calls itself Poth Company Brain, a truth-seeking AI agent for customer feedback. It unifies conversations, feedback, and customer…
- Company Website
- trydenta.com
- One-Liner
- AI back office for dental practices
- HQ Country
- United States
- Company Website
- isengardindustries.com
- One-Liner
- AI-powered precision munitions maker
- Product Description
- ISENGARD builds AI-powered precision munitions and unmanned strike systems for allied governments and defense partners. Its lineup spans sh…
- Company Website
- whitespacehq.ai
- One-Liner
- AI agents for wholesale distribution
- HQ Country
- United Kingdom
- Company Website
- 6thsense.dev
- One-Liner
- AI agent platform for developer workflows
- HQ Country
- United States
- Company Website
- dialoguslabs.com
- One-Liner
- Enterprise AI voice agents for operations
- HQ Country
- United States
- Company Website
- perceptronml.com
- One-Liner
- Event-driven real-world signal response engine
- HQ Country
- United States
- Company Website
- baudlabs.ai
- One-Liner
- Efficient AI chip and compiler stack
- Employee Count
- 1-10
- Company Website
- experientiallabs.ai
- One-Liner
- World models from agent telemetry traces
- Product Description
- Experiential Labs builds a world-model harness that reconstructs agent environments from production telemetry. The site says the system tur…
- Company Website
- operonsolutions.com
- One-Liner
- AI-powered manufacturing intelligence for plants
- HQ Country
- United States
- Company Website
- usebylaw.com
- One-Liner
- Runtime enforcement for AI agent actions
- HQ Country
- Canada
- Company Website
- edviroenergy.com
- One-Liner
- AI energy management for K-12 districts
- HQ Country
- United States
- Company Website
- greypointindustries.ca
- One-Liner
- Canadian defence startup building lethal man-deployable systems fully in Canada
- Employee Count
- 1-10
- Company Website
- molagri.com
- One-Liner
- Nature-inspired precision biopesticides
- HQ Country
- Canada
- Company Website
- verdantapp.com
- One-Liner
- AI-native permitting software for local government
- Product Description
- Verdant builds AI-native land-use permit management software for local governments. The platform covers resident intake, plan review and ma…
- Company Website
- prized.dev
- One-Liner
- AI-built internal tools from plain English
- HQ Country
- United States
- Company Website
- inkbox.ai
- One-Liner
- Identity layer for AI agents
- HQ Country
- United States
- Company Website
- os3robotics.com
- One-Liner
- Deployment-focused robotics with real-floor learning
- HQ Country
- United States
- Company Website
- petrarch.co
- One-Liner
- Marketplace for specialized AI training data
- HQ Country
- United States
- Company Website
- praxisrobotics.io
- One-Liner
- Egocentric robot training data capture
- Product Description
- Praxis says it captures how real work is done and hands it to the machines that will inherit it. The site presents egocentric recordings an…
- Company Website
- salemroboticsinc.com
- One-Liner
- Nuclear-native autonomy software for hazardous inspections
- Product Description
- Salem Robotics builds autonomy software for autonomous radiological surveys and inspections in hazardous nuclear environments. The platform…
- Company Website
- nebusec.ai
- One-Liner
- AI security research lab for code vulnerabilities
- HQ Country
- United States
- Company Website
- cosmicrobotics.com
- One-Liner
- AI-powered tools for construction and logistics
- HQ Country
- United States
- Company Website
- risklytics.ai
- One-Liner
- Per-parcel disaster risk pricing models
- HQ Country
- United States
- Company Website
- norirobotics.com
- One-Liner
- Bimanual home robots with remote teleoperation
- HQ Country
- United States
- Company Website
- goekpa.com
- One-Liner
- Rules-based S&P 500 trend investing
- HQ Country
- United States
- Company Website
- justinianai.com
- One-Liner
- AI government affairs firm
- Product Description
- Justinian describes itself as the first AI government affairs firm. It combines lobbyists and AI agents for policy monitoring, lobbying exe…
- Company Website
- robocurve.org
- One-Liner
- Forecasting physical automation and robot capability
- Product Description
- Robocurve is a Public Benefit Corporation that studies physical AI and robot capabilities. It independently evaluates robots and the models…
- Company Website
- amulet.so
- One-Liner
- Agentic post-sales intelligence platform
- HQ Country
- United States
- Company Website
- 83sciences.ai
- One-Liner
- AI-native research workspace for materials labs
- Product Description
- 83 Sciences builds an intelligence engine and workspace for scientific research, with a stated emphasis on materials scientists. The platfo…
- Company Website
- vestris.ai
- One-Liner
- AI processing unit for mortgage closing
- HQ Country
- United States
- Company Website
- screenpipe.com
- One-Liner
- Local-first workflow memory for AI agents
- Employee Count
- 1-10
- Company Website
- lemonlime.ai
- One-Liner
- AI knowledge layer for business teams
- HQ Country
- United States
- Company Website
- speko.ai
- One-Liner
- Voice AI gateway with benchmark routing
- HQ Country
- United States
- Company Website
- rindler.ai
- One-Liner
- Agent commerce infrastructure for AI agents
- Product Description
- Rindler is a translation layer between AI agents and the web. It exposes websites through a hosted MCP server that returns structured JSON,…
- Company Website
- withasync.com
- One-Liner
- Specialized AI agents for back-office work
- Product Description
- Async builds specialized AI agents that automate administrative and operational work inside existing company systems. The site says it audi…
- Company Website
- hyperprobe.co
- One-Liner
- Runtime debugging layer for AI agents
- HQ Country
- United States
- Company Website
- agnost.ai
- One-Liner
- Production conversation analysis for AI agents
- Product Description
- Agnost AI continuously analyzes production conversations from chat and voice systems. It identifies where users get stuck, repeat retries, …
- Company Website
- floracene.com
- One-Liner
- Medical device procurement optimization for independent surgery centers
- HQ Country
- United States
- Company Website
- rise-reforming.com
- One-Liner
- Biogas-to-chemicals modular reforming technology
- Product Description
- Rise Reforming converts stranded biogas from wastewater plants, farms, and landfills into chemicals on site. The company says its patent-pe…
- Company Website
- trope.ai
- One-Liner
- AI-native ERP implementation platform
- HQ Country
- United States
- Company Website
- conifer.build
- One-Liner
- Local-first inference router for AI models
- HQ Country
- United States
- Company Website
- earendil.io
- One-Liner
- Defense robotics for situational awareness
- Product Description
- Earendil Robotics builds defense robotics and vision systems for tactical users. Its product line includes soldier situational awareness ha…
- Company Website
- openrelay.inc
- One-Liner
- Distributed GPU cloud for inference
- Product Description
- OpenRelay runs production inference across a distributed network of GPUs. It positions itself as a resilient compute layer for AI applicati…
- Company Website
- skymerse.com
- One-Liner
- AI-powered flight planning for aviation professionals
- HQ Country
- United States
- Company Website
- provenmetal.com
- One-Liner
- Domestic PCB assembly with X-ray verification
- HQ Country
- United States
- Company Website
- alloovium.com
- One-Liner
- AI-native document intelligence for construction
- HQ Country
- United States
- Company Website
- zommalabs.com
- One-Liner
- Frontier computer-use agents for enterprise workflows
- HQ Country
- United States
- Company Website
- opentrade.live
- One-Liner
- Swipeable market research, backed by Y Combinator
- HQ Country
- United States
- Company Website
- usetorus.com
- One-Liner
- Engineering intelligence for capital projects
- Product Description
- Torus provides AI agents for capital projects that read P and IDs, HMBs, spec sheets, and related engineering documents. The system cross-r…
- Company Website
- litmushiring.com
- One-Liner
- AI technical interview pipelines from code
- HQ Country
- United States
- Company Website
- librabots.com
- One-Liner
- Y Combinator-backed solar installation robots
- Employee Count
- 11-50
- Company Website
- osseus.ai
- One-Liner
- Secure research brain for R&D teams
- Product Description
- Osseus connects existing research tools into a permissioned research brain for R&D teams. The platform combines permission-aware chat, back…
- Company Website
- alkera.ai
- One-Liner
- Data engineering agent with lineage
- HQ Country
- United States
- Company Website
- understudylabs.com
- One-Liner
- Production trace tuning for specialist open models
- HQ Country
- United States
- Company Website
- palettetechnology.com
- One-Liner
- Interactive multimodal generation platform
- Employee Count
- 1-10
- Company Website
- onecli.sh
- One-Liner
- Open-source credential gateway for AI agents
- Employee Count
- 1-10
- Company Website
- ooakdata.com
- One-Liner
- AI agents evaluated in real business workflows
- HQ Country
- France
- Company Website
- hoplite.sh
- One-Liner
- Keyboard-driven dashboard for coding agents
- HQ Country
- United States
- Company Website
- assemble.ai
- One-Liner
- Enterprise IT agents for system changes
- HQ Country
- United States
- Company Website
- hardwareintelligence.ai
- One-Liner
- Agent-native chip design toolchain
- HQ Country
- United States
- Company Website
- subvysion.com
- One-Liner
- AR mapping for underground utilities
- HQ Country
- United States
- Company Website
- notyfi.com
- One-Liner
- Live alerts for anything happening worldwide
- HQ Country
- United States
- Company Website
- illumelabs.ai
- One-Liner
- AI personal health and longevity companion
- HQ Country
- United States
- Company Website
- nex.ai
- One-Liner
- AI-powered context layer for customer data
- HQ Country
- United States
- Company Website
- rational.to
- One-Liner
- AI coworkers for accounting teams
- HQ Country
- United States
- Company Website
- aktoria.com
- One-Liner
- Robotics fleet teleoperation and data collection
- HQ Country
- United States
- Company Website
- instaplay.ai
- One-Liner
- Multiplayer AI game maker for browser games
- HQ Country
- United States
- Company Website
- axelrod.live
- One-Liner
- Operating layer for boutique hotels
- Product Description
- Axelrod runs daily hotel and resort operations inside existing systems and teams. It coordinates work across guests, rooms, rates, access, …
- Company Website
- daqstra.com
- One-Liner
- AI-native hardware R&D platform for engineers
- HQ Country
- United States
- Company Website
- codealmanac.com
- One-Liner
- Living wiki for codebase context
- HQ Country
- United States
- Company Website
- rapidfolio.com
- One-Liner
- AI operations for regulated finance
- Employee Count
- 1-10
- Company Website
- thebillow.ai
- One-Liner
- Voice AI for automating accounts receivable collections
- HQ Country
- United States
- Company Website
- bizmark.ai
- One-Liner
- Operating system for physical goods companies
- HQ Country
- United States
- Company Website
- belvedir.ai
- One-Liner
- Autonomous private AI for custom model training
- HQ Country
- United States
- Company Website
- donkey.trade
- One-Liner
- Factory-direct supply for US importers
- Product Description
- Donkey describes itself as a modern trading company for US importers. The homepage says buyers can send one photo, identify the factory tha…
- Company Website
- vendo.run
- One-Liner
- Open-source customization layer for SaaS products
- HQ Country
- United States
- Company Website
- manufacturingintelligence.org
- One-Liner
- AI-powered automated drawing review for manufacturers
- HQ Country
- United States
- Company Website
- kebra.ai
- One-Liner
- AI agents for field service shops
- Product Description
- Kebra presents itself as an AI native operating layer for field service companies. Its product turns technician job recordings into structu…
- Company Website
- rekursiv.ai
- One-Liner
- Autonomous AI Scientists for research
- Product Description
- rekursiv.ai builds autonomous systems of models that hypothesize, design experiments, run tests, and interpret results like research scient…
- Company Website
- lastaccountingcompany.com
- One-Liner
- Agent-native AI accounting firm for Finnish SMBs
- HQ Country
- United States
- Company Website
- getcomputable.com
- One-Liner
- Weekly GPU hour marketplace with instant liquidity
- HQ Country
- United States
- Company Website
- orvixo.ai
- One-Liner
- AI planning and scheduling for complex manufacturing
- HQ Country
- United Kingdom
- Company Website
- manifoldindustries.ai
- One-Liner
- Autonomous warehouse robots for pick operations
- Product Description
- Manifold Industries builds autonomous warehouse robots for case picking, trailer loading, unloading, and palletizing. The system combines w…
- Company Website
- shieldedglobal.com
- One-Liner
- External risk intelligence for margins
- Product Description
- Shielded connects internal business data with external events, prices, and regulatory changes. The platform maps how outside signals affect…
- Company Website
- olamlabs.ai
- One-Liner
- AI social games and benchmark arenas
- Product Description
- Olam Labs builds multiplayer simulation games where humans and AI agents compete in structured social environments. Its products include So…
- Company Website
- maingen.ai
- One-Liner
- RL environments for training AI on industrial operations
- HQ Country
- United States
- Company Website
- ego.ist
- One-Liner
- Portable personal memory layer for AI apps
- HQ Country
- United States
- Company Website
- propriorobotics.com
- One-Liner
- Autonomous robots for data center lifecycle tasks
- HQ Country
- United States
- Company Website
- gamgee.io
- One-Liner
- Personalized mRNA cancer vaccines for dogs
- HQ Country
- United States
- Company Website
- inductionlabs.com
- One-Liner
- AI agents for computer automation
- Employee Count
- 1-10
- Company Website
- blaise.new
- One-Liner
- AI system that replaces IT consultancies
- HQ Country
- Sweden
- Company Website
- avocasystems.com
- One-Liner
- Operational intelligence for radiology networks
- HQ Country
- United States
- Company Website
- locke.inc
- One-Liner
- Applied AI for government affairs
- Product Description
- Locke is an applied AI company that says it changes how companies and governments work together. Its first product, Locke Government Affair…
- Company Website
- usederya.com
- One-Liner
- Maritime planned maintenance tracker for ship managers
- HQ Country
- United States
- Company Website
- neuronindustries.com
- One-Liner
- iOS app development with 4.5-star average rating
- HQ Country
- United States
- Company Website
- zaplar.com
- One-Liner
- Real-time 3D configurator and AI upsells for hospitality event booking
- Employee Count
- 1-10
- Company Website
- agencytool.com
- One-Liner
- Reliable infrastructure to build, deploy, and manage real-world robots
- HQ Country
- United States
- Company Website
- waddlelabs.ai
- One-Liner
- LLM agents that control robots
- HQ Country
- United States
- Company Website
- atomarine.co
- One-Liner
- Floating nuclear-powered data centers at sea
- HQ Country
- United States
- Company Website
- lumeria.skin
- One-Liner
- At-home multispectral skin tracker with AI companion
- HQ Country
- United States
- Company Website
- pokerclubhub.com
- One-Liner
- Private browser poker with instant cashouts
- Product Description
- PokerClubHub is a browser-based private poker platform for playing in invite-only clubs without downloads. It supports No Limit Texas Hold'…
- Company Website
- traceforce.ai
- One-Liner
- On-device AI security for device fleets
- Product Description
- Traceforce is an AI security and control platform for devices, with visibility across browser AI, desktop apps, and CLI agents. It monitors…
- Company Website
- wondering.app
- One-Liner
- Personalized AI learning app for any topic
- HQ Country
- United Kingdom
- Company Website
- graphify.com
- One-Liner
- Open-source knowledge graph for AI coding assistants
- HQ Country
- United Kingdom
- Company Website
- synapsesemi.org
- One-Liner
- On-sensor AI image sensor lab
- Product Description
- Synapse Semiconductor describes itself as a frontier semiconductor research lab building senses for physical AI. It builds image sensors th…
- Company Website
- gutgutgoose.com
- One-Liner
- Science-backed personalised probiotics with 1000+ strains
- HQ Country
- Australia
- Company Website
- ae-dyn.com
- One-Liner
- Radio-wave camera seeing through walls with millimeter accuracy
- HQ Country
- United States
- Company Website
- tracerml.ai
- One-Liner
- YC-backed AI coordination research lab
- Product Description
- Tracer is a YC-backed research lab that studies coordinated intelligence for AI systems. The company turns that research into products that…
- Company Website
- trydock.ai
- One-Liner
- AI contract review for enterprise legal teams
- Product Description
- Dock appears to be a contract review product for legal and business teams, presented under the Dock brand at trydock.ai. The company’s publ…
- Company Website
- griprobotics.ai
- One-Liner
- Physical AI grippers for waste sorting
- Product Description
- Grip Robotics builds physical AI grippers for waste management and material handling. The company says its grippers perceive, adapt, and ma…
- Company Website
- hubble.ai
- One-Liner
- Patient-data intelligence layer for EHR access
- Product Description
- Hubble describes itself as the intelligence layer for patient information. It connects to EHRs, payers, and patient records through APIs, b…
- Company Website
- lamb-labs.com
- One-Liner
- Custom AI inference chips
- Product Description
- Lamb Labs builds custom chips for AI inference and says it converts autoregressive models into diffusion architectures. The company claims …
- Company Website
- decawork.ai
- One-Liner
- Agent control plane for IT teams
- Product Description
- Decawork is an agent control plane for IT teams that deploys, governs, and maintains AI agents across a company. The platform manages ident…
- Company Website
- ekholabs.com
- One-Liner
- Predictive intelligence for global logistics risk
- HQ Country
- United States
- Company Website
- joinmarble.ai
- One-Liner
- AI-native restaurant back-office OS
- Product Description
- Marble is the company formerly known as Truffle, and it positions itself as autonomous back of house software for restaurants. It covers in…
- Company Website
- gitcafe.dev
- One-Liner
- Independent git forge with native CLI
- Product Description
- GitCafe is a hosted git forge built by one team, including its own git implementation. The public site shows code browsing, diff viewing, p…
- Company Website
- atlia.com
- One-Liner
- AI-driven financial analytics for investment funds
- Product Description
- Atlia is a financial analytics platform leveraging AI technology to serve operator-style investment funds in private markets. The platform …
- Company Website
- hiloop.ai
- One-Liner
- Infrastructure for automated research via autoresearch agents
- HQ Country
- United States
- Company Website
- executor.sh
- One-Liner
- Open-source MCP gateway for AI agents
- HQ Country
- United States
- Company Website
- lucaiq.com
- One-Liner
- AI-native workflow platform for CPA firms
- HQ Country
- United States
- Company Website
- stratumindustries.co
- One-Liner
- AI agents clearing U.S. government application backlog
- HQ Country
- United States
- Company Website
- stoaexchange.com
- One-Liner
- Institutional marketplace for GPUs and AI hardware
- HQ Country
- United States
- Company Website
- getcoach.com
- One-Liner
- AI sales coach for in-person field reps
- HQ Country
- United States
- Company Website
- karalabs.ai
- One-Liner
- Engineered diamond wafers for advanced hardware
- HQ Country
- United States
- Company Website
- openvector.com
- One-Liner
- Turns security cameras into automated 24/7 workforce
- HQ Country
- United States
- Company Website
- tarebio.com
- One-Liner
- Vaccines for any cancer or infection
- HQ Country
- USA
- Company Website
- tash.cards
- One-Liner
- Investment platform for sports and trading cards
- HQ Country
- United States
- Company Website
- amorphiclabs.com
- One-Liner
- AI agents creating personalized product demo videos
- HQ Country
- United States
- Company Website
- tridentsecurity.io
- One-Liner
- AI web and API pentesting with cloud attack-path analysis
- HQ Country
- United States
- Company Website
- spaceflow.tech
- One-Liner
- AI-powered procurement orchestration with real-time risk prediction
- HQ Country
- United Kingdom
- Company Website
- trycarsignal.com
- One-Liner
- Smart OS for auto repair shops
- HQ Country
- United States
- Company Website
- standardmachines.com
- One-Liner
- AI training environments for chip design
- HQ Country
- United States
- Company Website
- caution.co
- One-Liner
- Verifiable compute platform for confidential, platform-agnostic systems
- Employee Count
- 1-10
- Company Website
- rasyn.ai
- One-Liner
- AI co-chemist that automates computational chemistry workflows
- HQ Country
- United States
- Company Website
- impact-drones.com
- One-Liner
- Autonomous interceptor drones for critical infrastructure defense
- HQ Country
- United States
- Company Website
- omanta.com
- One-Liner
- Personalized research lab for complex patients
- HQ Country
- United States
- Company Website
- heybuildbox.com
- One-Liner
- Agent analytics for real user outcomes
- HQ Country
- United States
- Company Website
- michiganhomehelp.com
- One-Liner
- Michigan-based home care and disability support
- HQ Country
- United States
- Company Website
- palisade-ai.com
- One-Liner
- AI that finds and fixes OS-level vulnerabilities across device fleets
- HQ Country
- United States
- Company Website
- agentfm.ai
- One-Liner
- Desktop app to hear and steer coding agents
- HQ Country
- United States
- Company Website
- ultrasonium.com
- One-Liner
- Advanced metal additive manufacturing for aerospace, defense, energy
- HQ Country
- United States
- Company Website
- arbital.xyz
- One-Liner
- Decentralized market making engine for perp DEXes
- HQ Country
- United States
- Company Website
- riften.ai
- One-Liner
- Earned Intelligence gateway routing LLM requests to lowest-cost model
- HQ Country
- United States
- Company Website
- chromie.dev
- One-Liner
- AI workspace for government contract capture and BD
- HQ Country
- United States
- Company Website
- useclick.ai
- One-Liner
- MCP providing external context beyond web search
- HQ Country
- United States
- Company Website
- radley.health
- One-Liner
- AI-native radiology practice
- HQ Country
- United States
- Company Website
- neuromorphic.vision
- One-Liner
- Embodiment-agnostic robot brain for physical industries
- HQ Country
- United States
- Company Website
- getqlo.com
- One-Liner
- AI that automates commercial insurance underwriting workflow
- HQ Country
- United States
- Company Website
- exosat.com
- One-Liner
- Zero US-part sovereign satellite constellation for D2C
- HQ Country
- Singapore
- Company Website
- dawnxr.com
- One-Liner
- Automatic robot cell fault diagnosis and recovery
- HQ Country
- United States
- Company Website
- hebbianrobotics.com
- One-Liner
- APIs for Physical AI data quality analysis
- HQ Country
- United States
- Company Website
- prodigy.markets
- One-Liner
- AI research lab training foundation models for quantitative trading
- HQ Country
- United States
- Company Website
- getaudun.com
- One-Liner
- AI-native debt collection with gentle automation
- HQ Country
- Norway
- Company Website
- jcode.sh
- One-Liner
- Open-source Rust terminal AI coding agent
- HQ Country
- United States
- Company Website
- erinys.ai
- One-Liner
- Launches and operates AI-native law firms
- HQ Country
- United States
- Company Website
- gopacific.ai
- One-Liner
- Mass-produced solar-powered waterless autonomous GPU data centers for desert and orbit
- HQ Country
- United Kingdom
- Company Website
- peer-freight.com
- One-Liner
- AI-native freight brokerage specializing in hard-to-move hazmat loads
- HQ Country
- United States
- Company Website
- mosaic.inc
- One-Liner
- Real-time shared workspace for teams and AI agents
- HQ Country
- United States
- Company Website
- enact.company
- One-Liner
- Generates robotics training data via full improvement loop
- HQ Country
- United States
- Company Website
- verdictmachine.com
- One-Liner
- AI firewall for companies moving money onchain
- HQ Country
- Israel
- Company Website
- financialdatasets.ai
- One-Liner
- Stock market API with extensive financial data
- Product Description
- Financial Datasets provides a stock market API that offers real-time and historical financial data for over 30,000 tickers spanning more th…
- Company Website
- shiraz.ai
- One-Liner
- Robots that learn new factory tasks from a single human demonstration
- HQ Country
- United States
- Company Website
- trynearby.com
- One-Liner
- Local influence network connecting businesses with nearby creators
- HQ Country
- United States
- Company Website
- movingatoms.ai
- One-Liner
- World models that train and evaluate robots in virtual physics
- HQ Country
- United States
- Company Website
- heytenor.com
- One-Liner
- Manages AI workers with roles, managers, and measurable outcomes
- HQ Country
- United States
- Company Website
- edotenv.com
- One-Liner
- Market-derived RL environments training agents for quant research
- HQ Country
- United States
- Company Website
- magmahq.ai
- One-Liner
- Monetizes AI agent interaction data for AI labs
- HQ Country
- United States
- Company Website
- princeps.dev
- One-Liner
- AI-native insurance for the compute economy
- HQ Country
- United Kingdom
- Company Website
- toven.ai
- One-Liner
- AI agents for compliance at institutional brokerages
- HQ Country
- United States
- Company Website
- getpennant.ai
- One-Liner
- AI-native proxy voting and governance intelligence for institutional investors
- HQ Country
- United States
- Company Website
- thefamiliarlab.com
- One-Liner
- Real-time voice translation and lip-sync dubbing lab
- Employee Count
- 1-10
- Company Website
- marengox.com
- One-Liner
- AI-native engineering firm accelerating data center development
- HQ Country
- United States
- Company Website
- deepreach.ai
- One-Liner
- Expert-driven evaluation as a service for enterprise AI
- HQ Country
- United States
- Company Website
- mochi.tv
- One-Liner
- Mobile-first 1-minute anime shorts produced daily with AI
- HQ Country
- United States
- Company Website
- mentlio.com
- One-Liner
- Engineering intelligence platform for the AI-coding era
- HQ Country
- United States
- Company Website
- dipolelabs.com
- One-Liner
- Photonic hardware for AI and quantum infrastructure
- HQ Country
- United States
- Company Website
- meteoric.earth
- One-Liner
- Drones that clear clouds over solar farms
- HQ Country
- United States
- Company Website
- waybill.to
- One-Liner
- Managed procurement and inventory for hardware teams
- HQ Country
- India
- Company Website
- akonlabs.com
- One-Liner
- Builds GitNexus, the nervous system for agent context
- HQ Country
- United States
- Company Website
- veltha.ai
- One-Liner
- AI claims adjuster for regulated insurance backed by YC
- HQ Country
- United States
- Company Website
- tarifflo.com
- One-Liner
- AI-powered HTS classification with 55% tariff reduction
- Employee Count
- 11-50
- Company Website
- lyon.so
- One-Liner
- Private foundation models trained on customer event data
- HQ Country
- United States
- Company Website
- bernardhq.com
- One-Liner
- AI-powered operating system for the skilled trades helping appliance technicians.
- HQ Country
- United States
- Company Website
- palisade.run
- One-Liner
- Personal AI sales agent for every marketplace visitor
- HQ Country
- United States
- Company Website
- wondertx.ai
- One-Liner
- Extrapolative AI biotech replacing injections with pills
- HQ Country
- United States
- Company Website
- pingdream.com
- One-Liner
- Pocket-sized battery-powered AI cameras that catch asset damage
- HQ Country
- United States
- Company Website
- evergrovelabs.com
- One-Liner
- Voice AI agents purpose-built for workers' compensation
- HQ Country
- United States
- Company Website
- touchyapp.com
- One-Liner
- Personal on-iPhone AI assistant that talks to your apps
- HQ Country
- United States
- Company Website
- kandorlabs.com
- One-Liner
- AI-powered medical billing for specialty clinics
- Employee Count
- 1-10
- Company Website
- massmagnetics.com
- One-Liner
- Domestic recycled rare-earth permanent magnets for DFARS defense compliance
- HQ Country
- United States
- Company Website
- vernius.systems
- One-Liner
- Drop-in autonomy modules turning FPV drones into autonomous interceptors
- HQ Country
- United States
- Company Website
- standardmedical.com
- One-Liner
- Primary care clinic where AI earns clinical autonomy
- HQ Country
- United States
- Company Website
- aerogensystems.com
- One-Liner
- Point-of-use contamination destruction for semiconductor manufacturing
- HQ Country
- United States
- Company Website
- callbook.ai
- One-Liner
- AI-powered 24/7 phone system for Spanish-speaking businesses
- HQ Country
- Colombia
- Company Website
- grocalo.com
- One-Liner
- AI second brain that runs creator content distribution and engagement
- HQ Country
- United States
- Company Website
- onmarker.com
- One-Liner
- AI-native consultancy embedding custom AI agents into operations
- HQ Country
- United States
- Company Website
- playsnappoker.com
- One-Liner
- First social poker app with a built-in feed
- HQ Country
- United States
- Company Website
- hilstart.io
- One-Liner
- Autonomous hardware test and firmware development agent
- HQ Country
- United States
- Company Website
- trystudio.ai
- One-Liner
- Consumer decision simulation platform backed by Y Combinator
- HQ Country
- United States
- Company Website
- allia.health
- One-Liner
- AI-native clinical group for behavioral health practices
- HQ Country
- United States
- Company Website
- coarena.ai
- One-Liner
- Live blind arena for real-world computer-use agent evals
- HQ Country
- United States
- Company Website
- edgerun.com
- One-Liner
- Military exoskeletons that increase soldier strength and endurance
- HQ Country
- United States
- Company Website
- spectreintelligence.ai
- One-Liner
- independent research and trading firm that trains AI traders
- HQ Country
- United States
- Company Website
- tryopentag.com
- One-Liner
- Model-agnostic AI teammate for Slack and Microsoft Teams
- HQ Country
- United States
- Company Website
- ethos-space.com
- One-Liner
- Building spaceports on the Moon and Mars
- HQ Country
- United States
- Company Website
- onetriangle.ai
- One-Liner
- KV cache transfer inference engine cutting costs 20%
- HQ Country
- United States
- Company Website
- mostrobotic.com
- One-Liner
- Robotics research lab building autonomous evaluation rig for robot learning
- HQ Country
- United States
- Company Website
- cuebench.dev
- One-Liner
- RL environments for scientific reasoning and performance engineering
- HQ Country
- United States
- Company Website
- frontier.site
- One-Liner
- Biocomputing company growing large-scale biological neural tissue
- HQ Country
- United Kingdom
Company | Company Website | One-Liner | HQ Country | Employee Count | Founding Year | Product Description | YC Page | YC Industry | YC Partner | Functional Type | Extruct Industry | LinkedIn Profile | GitHub URL | Business Model v4 | Extruct Category | Sub-cluster | AI Pattern | Builds Hardware | Funding Verified | Delivery Model | Number of Founders | Founders LinkedIn |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AI job application agent for seekers | United States | 1-10 | 2026 | Tsenta builds an AI agent that monitors more than 50,000 company career pages and submits tailored job applications. It supports application workflows through Workday, Greenhouse, Lever, Ashby, Chrome, iMessage, WhatsApp, and CLI or MCP tools. The product targets applicants who want faster submissio | Consumer, Recruiting, HR Tech | Jared Friedman sources: 1 | Recruiting Software, AI Research, Skills Training & Career Development Platforms | – | – | AI-native service | Consumer | job application automation | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Eval platform for autonomous software | United States | 1-10 | 2026 | Archal is an eval platform for autonomous software that tests agents against clones of real services. It runs realistic scenarios on stateful clones, then records traces, criteria, and evidence for debugging and review. The company says it supports agent testing across common developer tools and is | B2B, Infrastructure | Ankit Gupta sources: 1 | Dev tools for AI Agents, API Development & Integration Platforms, Software Testing & QA Automation Tools | Analytics | – | – | Developer infrastructure | DevTools | API testing platform | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | |||
AI-native layer for SCADA systems | United States | 1-10 | 2025 | Control Seat is an AI-native intelligence layer that sits on top of existing SCADA systems. It connects live industrial data, supports real-time analysis, and adds AI-assisted dashboards, automation, and root-cause workflows. The company reports sub 100 millisecond latency, 10,000-plus tags per seco | Industrials | Jared Friedman sources: 1 | Analytics & BI: Data analytics, Cloud/DevOps Tools, Workflow automation | Analytics, Asset Management, Consumer, Engineering, Healthcare IT, Manufacturing, Operations, Productivity, Supply Chain | – | AI-enhanced software | Manufacturing | real-time dashboards | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI-native defense supply chain layer | United States | 1-10 | 2025 | GUILD builds the operating layer between government demand and manufacturing execution for defense production. Its site describes workflows for market intelligence, machine integration, packaging, testing, predictive analytics, and logistics intelligence. The company also states security practices m | Industrials, Defense | – | AI Research, Dev tools for AI Agents | Analytics, Productivity | – | – | Developer infrastructure | DevTools | experiment management toolkit | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | |||
Log compression for AI incident agents | United States | 1-10 | 2026 | Codag builds infrastructure tooling that compresses raw logs into schema-valid incident capsules for AI agents. The system uses deterministic log templating, MCP-compatible delivery, and cited outputs tied to exact log lines. Codag positions the product for agentic debugging rather than human dashbo | B2B, Infrastructure | Harshita Arora sources: 1 | Analytics & BI: Data analytics, Dev tools for AI Agents, Workflow automation | Analytics, Infrastructure, Logistics | Developer infrastructure | DevTools | log data summarization | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 1 | 1 founder | |||||
AI order-to-cash workforce for enterprises | United Kingdom | 1-10 | 2026 | Rex builds AI agents for order-to-cash operations at global enterprises. The product handles inbox triage, portals, cash application, and exception routing before receivables stall. It also exposes operational reporting through alerts, daily status views, and dispute tracking. | B2B, Finance and Accounting | Vivian Midha Shen sources: 1 | Payments & FinOps Platforms, Workflow automation, Accounting Tech | Finance, Analytics, Automotive, B2B, Consumer Finance, Operations, Payments, Productivity | – | AI-enhanced software | Fintech | accounts receivable automation | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Structured web data for AI agents | United States | 1-10 | 2026 | Context.dev provides a web scraping API for AI agents and LLM pipelines. Its platform combines website crawling, structured extraction, and brand intelligence across domains. The company says it is backed by Y Combinator and serves more than 5,000 developers. | B2B, Infrastructure | – | Skills Training & Career Development Platforms, Education Tech | Education, Analytics, Consumer, Content | – | – | AI-enhanced software | – | coding bootcamps | AI-native application | Software only | – | Self-serve SaaS / software | 1 | 1 founder | |||
AI agents for real estate contracts | United States | 1-10 | 2025 | RealPact automates real estate transactions with AI agents that pull MLS, deed, tax, and property data into contracts. It describes a workflow that drafts, reviews, and sends documents in minutes, while also positioning the product as an AI operating system for brokerages. The company reports contra | Real Estate and Construction, Housing and Real Estate | Jon Xu sources: 1 | Workflow automation | – | – | AI-native service | Blue Collar SaaS | real estate automation | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI-native agent suite for GP clinics in Australia | Australia | 1-10 | 2024 | Care GP delivers AI-powered automation for GP clinic operations, focusing on document filing, voice-based appointment management, and billing. Agents are designed specifically for Australian healthcare regulations and workflows. The platform is integrated with existing systems and operates with full | Healthcare | Tyler Bosmeny sources: 1 | AI Research, HR Software, Workflow automation, Healthcare Operations & Revenue Cycle Management | – | – | AI-enhanced software | Health | clinic automation tools | AI-native application | Software only | – | Self-serve SaaS / software | 1 | 1 founder | ||||
AI agent debit cards for single-use payments | United States | 1-10 | – | Agentcard provides single-use virtual cards for AI agents, letting agents pay for purchases without exposing real card details. The homepage says users approve every card and every charge, and the cards work with ChatGPT, Claude Desktop, and OpenClaw. The company is backed by Y Combinator and offers | Fintech | Tyler Bosmeny sources: 1 | Payments & FinOps Platforms | Fintech, Payments | – | Fintech | Fintech | virtual payment cards | AI agent for a vertical | Software only | – | Developer platform / API / infra | 1 | 1 founder | ||||
AI company brain for company knowledge | – | – | – | Cerenovus aggregates company files, emails, Slack messages, spreadsheets, and meeting notes into a single markdown knowledge graph. The Y Combinator page describes native AI-agent integration and a system that maps the company to infer operational inefficiencies and improvements. It was founded in 2 | B2B | Tyler Bosmeny sources: 1 | Collaboration/Productivity, Analytics & BI: Data analytics, Workflow automation | Analytics, Productivity | – | – | DevTools | Workflow automation tools | – | – | – | – | 1 | 1 founder | ||||
Backed by Y Combinator for persistent AI VMs | United States | 1-10 | 2026 | machine0 provides persistent NixOS and Ubuntu virtual machines with preinstalled tools, dedicated compute, static IPs, and per-minute billing. The product supports start, suspend, snapshot, and resume workflows, plus golden images, clones, optional GPUs, and HTTPS endpoints on subdomains such as .ma | B2B, Infrastructure | Brad Flora sources: 1 | Cloud/DevOps Tools | – | – | – | Developer infrastructure | DevTools | persistent virtual machines | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 1 | 1 founder | |||
Health benefits platform for ambitious employers | United States | 1-10 | 2026 | Prescience sells a health benefits platform for employers, with a Prescience Platinum Plan and member-facing care navigation. The site describes predictive care routing, a 24/7 AI Companion, and MD-led support alongside employer administration for claims, COBRA, ACA filings, payroll sync, and plan r | Healthcare | Ankit Gupta sources: 1 | HR Software, Health Data Integration & Interoperability Platforms, Healthcare Operations & Revenue Cycle Management | Healthcare, Fintech, Human Resources, Insurance | – | Fintech | Health | health benefits platform | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Building a physical internet for aviation infrastructure | United States | 1-10 | 2024 | Hop Aero is a stealth-mode startup focused on developing a physical internet for aviation infrastructure. The company aims to create a network of interconnected aviation components that enable real-time data exchange and operational efficiency. No public product details or customer information are a | Industrials, Defense | – | – | – | – | Hardware | Hardware | drone delivery systems | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
Shared memory layer for AI agents | United States | 1-10 | 2026 | Glen is a memory system for AI agents that stores and retrieves organization-wide knowledge. It is built for teams that want agents to read from and write to a shared memory layer. The product runs in production and is used for sensitive organizational memory across functions. | B2B, Productivity | Jared Friedman sources: 1 | AI Research, Collaboration/Productivity, Workflow automation | – | – | AI-enhanced software | DevTools | shared memory system | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 1 | 1 founder | ||||
Quality-based pricing for AI outputs | United Kingdom | 1-10 | 2026 | Touchmark prices AI products by evaluating output quality instead of counting tokens. Its TypeScript SDK, @touchmark/sdk, records sessions, emits events such as model outputs and code diffs, and returns quality-adjusted prices through separate valuations. The company is backed by Y Combinator and pr | B2B, Infrastructure | Brad Flora sources: 1 | AI Research, Dev tools for AI Agents | – | – | – | Developer infrastructure | DevTools | quality-based pricing | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | |||
Federal-grade geospatial ground truth for AI | United States | 1-10 | 2026 | Mireye provides AI agents with sourced geospatial context for any US coordinate, including terrain, land cover, buildings, water, and risk data. Its product, Mireye Earth, returns cited answers and timestamped fields through HTTP endpoints and an MCP server. The company says it is backed by Y Combin | B2B, Infrastructure | Jon Xu sources: 1 | Analytics & BI: Data analytics, AI Research, Dev tools for AI Agents | – | – | Developer infrastructure | DevTools | geospatial data API | AI agent for a vertical | Software only | – | Developer platform / API / infra | 1 | 1 founder | ||||
Agentic OS for e-commerce logistics | – | – | – | Pango is an Agentic OS for e-commerce operations that automates delivery, tracking, returns, transport, and customer support. The company describes its product as an autonomous digital employee and an intelligent operating system for e-commerce logistics. It is backed by Y Combinator and says it aut | B2B, Retail | Gustaf Alstromer sources: 1 | – | Logistics | – | AI-native service | Manufacturing | e-commerce logistics automation | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI operating system for structured credit | United States | 1-10 | 2025 | Levocred builds an AI platform for structured credit teams managing facilities, borrowing bases, and covenant oversight. The product turns loan tapes into lender-ready PDFs, produces credit memos, and centralizes cash and facility data across portfolios. The company says it is backed by Y Combinator | Fintech | Brad Flora sources: 1 | Payments & FinOps Platforms, Analytics & BI: Data analytics, HR Software, Other | Fintech | – | Fintech | Fintech | structured credit tools | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI-native back office for restaurants | – | – | – | Truffle is an AI-native operating system for hospitality that the site describes as the autonomous back of house for restaurants. It combines procurement, scheduling, inventory, menu, and financial workflows with computer vision, voice AI, and document extraction. The company says restaurants can go | B2B | Harj Taggar sources: 1 | HR Software, Workflow automation, Analytics & BI: Data analytics, Other | B2B | – | AI-native service | Blue Collar SaaS | back-of-house automation | AI-native application | Software only | – | Self-serve SaaS / software | 3 | 3 founders | ||||
Business development brain for law firms | United States | 1-10 | 2026 | Osmaura is a software product for law firms that scans the web, news, and firm data. It identifies pitching and cross-sell opportunities, then routes each one to the right partner. The company says it learns how a firm works and helps with daily business development tasks. | B2B | Jon Xu sources: 1 | CRM Platforms, Sales Enablement Tools, Marketing & Advertising Tech, Recruiting Software, HR Software, Payments & FinOps Platforms, Analytics & BI: Data analytics, Cloud/DevOps Tools, Collaboration/Productivity, Commerce Platforms, Security & Compliance Tools, Other, Customer Support, Backoffice aut | – | – | AI-native service | Legal | CRM Platforms | AI-native application | – | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
Agent-native research for investors | United Kingdom | 1-10 | 2026 | LATO runs primary and secondary research for investors, combining interviews, public data, and a fund’s internal knowledge. It turns that material into commercial studies that users can question, simulate, and update with follow-up queries. The company describes its system as an agent-native researc | B2B | Gustaf Alstromer sources: 1 | Analytics & BI: Data analytics, Other | – | – | AI-enhanced software | Other | research simulation platform | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI-powered K-12 mastery learning | – | – | – | Bloomy is an AI-powered, competency-based learning platform for K-12 students. It combines personalized learning journeys, Socratic tutoring, and standards-aligned lessons with teacher dashboards. The site positions Bloomy for schools and families, with examples spanning grades 5 through 12. | Education | Tyler Bosmeny sources: 1 | Education Tech, AI Research | – | – | AI-enhanced software | Consumer | competency-based learning | AI-native application | Software only | – | Self-serve SaaS / software | 1 | 1 founder | ||||
Autonomous prediction-market trading agents | – | 1-10 | 2026 | Blueprints builds autonomous agents for creating and running prediction-market strategies on Polymarket. The product combines a visual strategy builder, an AI co-pilot, live execution, and an MCP server for AI coding environments. The company describes the system as an operating layer for automated | Fintech, Consumer Finance | Vivian Midha Shen sources: 1 | Analytics & BI: Data analytics, Sales Enablement Tools, Other | – | – | – | Fintech | Fintech | prediction market agents | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||
AI work memory for team tools | United States | 1-10 | 2026 | Shepherd connects Slack, email, meetings, and code into one indexed company memory. It turns team conversations and source material into draft replies, bug filings, and links for approval. The product is currently in early release on macOS and is backed by Y Combinator. | B2B | Diana Hu sources: 1 | Collaboration/Productivity, Workflow automation, Analytics & BI: Data analytics, Other | Productivity | – | AI-enhanced software | DevTools | team communication indexer | AI-native application | Software only | – | Self-serve SaaS / software | 3 | |||||
Harvests high-quality training data for robotics | – | 1-10 | – | Markov specializes in collecting high-quality training data for robotics through human-in-the-loop motion capture, tele-operation, simulation control, and labeling. Their human-based data collection approach ensures precision and context-awareness in physical AI development. The company operates wit | B2B, Infrastructure | Harshita Arora sources: 1 | AI Research, Robotics, Other | Robotics | – | Marketplace | Hardware | training data for robotics | AI infrastructure / tooling | Software only | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
Warm introductions for elite GTM talent in NYC & SF startups | – | 1-10 | – | TalentPluto connects elite tech sales talent with top startups in NYC and SF through warm introductions. It offers a private, curated network with tailored role matching and fast-track interview access. The platform has processed 1,620 candidate conversations and made 500+ introductions. | B2B, Recruiting and Talent | Brad Flora sources: 1 | Recruiting Software, HR Software | Sales, Human Resources, Marketing, Engineering | – | Marketplace | CRM & Sales | talent matchmaking | Not primarily AI | Software only | – | Marketplace | 3 | 3 founders | ||||
AI-native health insurance decision graph | – | 1-10 | – | Insurf builds AI-native infrastructure for U.S. health insurance decisions and claim appeals. Its products model year-long plan costs, denial risk, and appeal packets using cited source documents and version-pinned coverage policies. The company says it is backed by Y Combinator and is in a pre-Demo | Healthcare | Gustaf Alstromer sources: 1 | AI Research, Health Data Integration & Interoperability Platforms, Healthcare Operations & Revenue Cycle Management, Insurance tech | – | – | AI-native service | Health | cost modeling tools | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Biological compute using living neurons | – | 1-10 | – | Parasma builds biological compute systems using living neurons as the computational substrate. The company says it writes algorithms and infrastructure that turn living neural systems into programmable compute, and it has demonstrated cultured neurons playing Doom. Parasma says it is backed by Y Com | B2B, Infrastructure | Tyler Bosmeny sources: 1 | AI Research, Other | – | – | Biotech | Other | biological computing systems | Hardware with AI | Software only | – | Developer platform / API / infra | 1 | 1 founder | ||||
Predictive drug-response models for biotech | – | – | – | Atlas Discovery builds foundation models of patient drug response using pre-clinical and clinical data. Its research describes predicting treatment response from baseline biopsies and modeling single-cell biology with discrete latent codes. The company says it aims to improve trial design and identi | Healthcare, Drug Discovery and Delivery | Ankit Gupta sources: 1 | AI Research, Analytics & BI: Data analytics, Healthcare Operations & Revenue Cycle Management | Drug Discovery | – | Biotech | Health | patient response models | Foundation model / frontier research | Software only | – | Developer platform / API / infra | 2 | 2 founders | ||||
Startup banking with FDIC-protected accounts | United States | 1-10 | 2026 | Florin offers an operating account for startups, combining accounts, cards, treasury, bill pay, and concierge support. The homepage says users can open an account in minutes and mentions extended FDIC protection across partner banks. The company positions itself as banking that helps startups move f | Fintech | Ankit Gupta sources: 1 | Payments & FinOps Platforms, HR Software, Other | Fintech | – | Fintech | Fintech | startup banking solutions | Not primarily AI | Software only | – | Self-serve SaaS / software | 3 | 3 founders | ||||
Document intelligence for MEP contractors | – | – | – | FlowManual reads contract, specification, bid, and invoice documents for HVAC and MEP contractors. It flags scope items, price references, deadlines, insurance requirements, exclusions, and price changes on the exact line. The product offers first-read review, bid-versus-contract comparison, and on- | Real Estate and Construction, Construction | Gustaf Alstromer sources: 1 | Other | – | – | AI-enhanced software | Manufacturing | document analysis tool | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Truth-seeking AI for customer feedback | – | – | – | Poth Labs calls itself Poth Company Brain, a truth-seeking AI agent for customer feedback. It unifies conversations, feedback, and customer data into a searchable customer brain for product, growth, and leadership teams. The homepage says the product is backed by Y Combinator. | B2B | Ankit Gupta sources: 1 | Analytics & BI: Data analytics, Customer Support, Sales Enablement Tools | Analytics, Consumer, Fintech, Human Resources, Operations, Productivity, Sales | – | AI-enhanced software | CRM & Sales | customer feedback analysis | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI back office for dental practices | United States | 1-10 | 2025 | Denta builds AI tools for dental organizations and describes itself as the first practice management system that runs the back office. The site presents Denta Analytics and a LiveAnalytics dashboard for tracking collections, production, accounts receivable over 30 days, and hygiene reappointment met | Healthcare, Healthcare IT | Jared Friedman sources: 1 | CRM Platforms, Analytics & BI: Data analytics, HR Software, Other | – | – | AI-enhanced software | Health | dental practice management | AI-native application | Software only | – | Self-serve SaaS / software | 1 | 1 founder | ||||
AI-powered precision munitions maker | – | – | – | ISENGARD builds AI-powered precision munitions and unmanned strike systems for allied governments and defense partners. Its lineup spans short-range anti-tank, mid-range attack, deep-strike, and unmanned combat aircraft systems. The company says its systems are combat-proven, operate in GNSS-denied | Industrials, Defense | Gustaf Alstromer sources: 1 | AI Research, Robotics, Other | – | – | – | Hardware | Hardware | precision munitions | Hardware with AI | Hardware / physical product | USD 15,000,000 | Hardware | 1 | 1 founder | |||
AI agents for wholesale distribution | United Kingdom | 1-10 | 2026 | Whitespace builds AI agents for wholesale distributors that analyze business data, forecast demand, and recommend inventory order quantities. The site describes it as an AI operating system for wholesale distribution, with workflows covering order entry, quotes, customer queries, accounting, pricing | B2B, Supply Chain and Logistics | Jon Xu sources: 1 | AI Research, Analytics & BI: Data analytics, Workflow automation | – | – | – | AI-enhanced software | Manufacturing | demand forecasting agents | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | ||||
AI agent platform for developer workflows | United States | 1-10 | 2026 | 6th Sense appears to build AI software for developer and engineering workflows, based on its product domain and brand presentation. The site content available here does not provide enough verified detail to identify specific proprietary features, customer segments, or measurable market traction. No | Industrials, Manufacturing and Robotics | Tyler Bosmeny sources: 1 | – | Productivity | – | Hardware | Hardware | tactile capture hardware | Hardware with AI | Hardware / physical product | – | Hardware | 3 | 3 founders | ||||
Enterprise AI voice agents for operations | United States | 1-10 | 2025 | Dialogus builds enterprise-grade AI voice agents that answer, resolve, route, and document customer conversations. The system combines telephony, workflow execution, CRM updates, human escalation, and audit-ready reporting across live voice operations. The company says it is backed by Y Combinator a | B2B, Infrastructure | Ankit Gupta sources: 1 | AI Research, Customer Support | – | – | AI-native service | DevTools | AI voice agents | AI-native application | Software only | – | Self-serve SaaS / software | 3 | |||||
Event-driven real-world signal response engine | United States | 1-10 | 2026 | Perceptron ML builds an event-driven engine that turns real-world signals into actions within minutes. The site describes trigger-based workflows that launch responses after events such as data breaches, new RFPs, listings, or regulatory filings. It is backed by Y Combinator. | B2B | Jared Friedman sources: 1 | Workflow automation, Analytics & BI: Data analytics, AI Research | – | – | – | AI-enhanced software | DevTools | event-driven notifications | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||
Efficient AI chip and compiler stack | – | 1-10 | 2026 | Baud builds hardware and software for training and serving frontier AI with lower compute overhead. Its core system includes an arithmetic representation that compresses neural networks without loss, plus an ASIC architecture claimed to run that representation 100x more efficiently than incumbent ap | Industrials | Diana Hu sources: 1 | AI Research, Dev tools for AI Agents | – | – | Hardware | Hardware | lossless compression ASIC | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
World models from agent telemetry traces | – | – | – | Experiential Labs builds a world-model harness that reconstructs agent environments from production telemetry. The site says the system turns usage signals into realistic simulations and supports recursive self-improvement across domains. Its research page also describes continual learning as a serv | B2B, Infrastructure | Diana Hu sources: 1 | AI Research, Dev tools for AI Agents | – | Developer infrastructure | DevTools | simulation infrastructure | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | |||||
AI-powered manufacturing intelligence for plants | United States | 1-10 | 2026 | Operon builds AI systems for industrial and process manufacturing, with a strong emphasis on P&ID recognition and engineering-document intelligence. Its site says the platform extracts diagram data at 97% accuracy, deploys in under six weeks, and supports custom agents for document processing, compl | Industrials | Jon Xu sources: 1 | AI Research, Manufacturing, Cloud/DevOps Tools, Workflow automation | – | AI-enhanced software | Manufacturing | P&ID intelligence | AI-native application | Software only | – | Self-serve SaaS / software | 1 | 1 founder | |||||
Runtime enforcement for AI agent actions | Canada | 1-10 | 2026 | Bylaw enforces AI agent tool calls in real time before sensitive actions execute. Its runtime gate checks evidence, logs decisions, and creates auditable trails for agent actions. The company also offers a deterministic policy engine and trace analysis for failed evidence checks. | B2B, Infrastructure | Ankit Gupta sources: 1 | Compliance Tech, AI Research, Dev tools for AI Agents | – | – | Developer infrastructure | DevTools | AI governance tools | AI infrastructure / tooling | Software only | – | Self-serve SaaS / software | – | – | ||||
AI energy management for K-12 districts | United States | 1-10 | – | Edviro is a B2B SaaS platform for K-12 school districts that tracks energy use across facilities. It uses AI agents to identify anomalies, delegate fixes to facilities staff, and verify savings through measurement and verification. The platform also simulates operational and capital changes, with pi | B2B, Infrastructure | Jared Friedman sources: 1 | Analytics & BI: Data analytics, Cloud/DevOps Tools, Other | B2B | – | AI-enhanced software | Other | energy management platform | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Canadian defence startup building lethal man-deployable systems fully in Canada | – | 1-10 | 2025 | Greypoint Industries designs and manufactures lethal, man-deployable systems for defence applications. The company leverages warfighter experience and elite engineering to deliver full-spectrum design and manufacturing entirely within Canada. Products are engineered for operational effectiveness and | Industrials, Defense | Tyler Bosmeny sources: 1 2 | Other | Manufacturing | – | Hardware | Hardware | autonomous defense hardware | Hardware with AI | Hardware / physical product | – | Hardware | 3 | 3 founders | ||||
Nature-inspired precision biopesticides | Canada | 1-10 | 2026 | Molagri develops precision biopesticides for crop protection and presents them as safe for humans, pollinators, and the environment. The homepage positions the company around nature-inspired agricultural inputs rather than conventional chemical crop protection. The company says it is backed by Y Com | Industrials, Agriculture | Tyler Bosmeny sources: 1 | – | Agriculture | – | Biotech | Manufacturing | precision biopesticides | Not primarily AI | Software only | – | – | 2 | 2 founders | ||||
AI-native permitting software for local government | – | – | – | Verdant builds AI-native land-use permit management software for local governments. The platform covers resident intake, plan review and markup, hearings, commission votes, ordinance research, and benchmarking against peer jurisdictions. YC lists the company as founded in 2026, in the Summer 2026 ba | Government | Jared Friedman sources: 1 | Other | – | – | AI-native service | Other | land-use permitting software | AI-native application | Software only | – | Self-serve SaaS / software | 2 | |||||
AI-built internal tools from plain English | United States | 1-10 | 2026 | Prized builds internal tools from plain-English workflow descriptions, then AI agents assemble software on live production data. The product includes approved connectors, scoped permissions, one-click deployment, and full audit logs for controlled releases. The site shows example tools such as renew | B2B, Engineering, Product and Design | Ankit Gupta sources: 1 | Workflow automation, Collaboration/Productivity, Other | – | – | – | AI-enhanced software | DevTools | internal tools builder | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||
Identity layer for AI agents | United States | 1-10 | 2025 | Inkbox provides an identity and communication layer for AI agents. It assigns agents email, phone, iMessage, and internet addresses, while adding persistent inboxes, tunnels, and secure vaults. The product is positioned for agents that need durable identities and cross-channel conversation history. | B2B, Infrastructure | Tyler Bosmeny sources: 1 | AI Research, Dev tools for AI Agents, Collaboration/Productivity | Analytics, Fintech, Human Resources, Marketing, Operations, Sales, Security, Consumer Electronics, Consumer Finance, Healthcare IT, Engineering, Education, Consumer, B2B | Developer infrastructure | DevTools | AI Agent Identity Layer | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 3 | 3 founders | |||||
Deployment-focused robotics with real-floor learning | United States | 1-10 | 2025 | OS3 is a deployment-focused robotics company that builds its hardware and models together. The company says its robot learns from internet video, first-person human footage, and limited robot data. It says the system is already deploying in hospitality and is structured to support deployments in und | Industrials, Manufacturing and Robotics | Gustaf Alstromer sources: 1 | Robotics, AI Research | – | – | – | Hardware | Hardware | hospitality robots | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | |||
Marketplace for specialized AI training data | United States | 1-10 | 2026 | Petrarch runs a marketplace for specialized AI training data and sources proprietary datasets from wind-downs and legacy businesses. It certifies and anonymizes those datasets, then brokers them to AI buyers. The company says its pipeline handles documents, images, audio, and mixed media, and it is | B2B | Vivian Midha Shen sources: 1 | AI Research, Other | Analytics, Fintech, Healthcare IT, Human Resources, Marketing, Operations, Productivity, Sales, Security, Supply Chain | – | Marketplace | Other | proprietary training data | AI infrastructure / tooling | Software only | – | Marketplace | 3 | 3 founders | ||||
Egocentric robot training data capture | – | – | – | Praxis says it captures how real work is done and hands it to the machines that will inherit it. The site presents egocentric recordings and live reconstruction with a ZED 2i head camera and wrist sensors. It shows industrial contexts including diamond, refinery, assembly, residential, and pharmaceu | Industrials | Diana Hu sources: 1 | AI Research, Robotics, Workflow automation | Robotics | – | – | Hardware | Hardware | egocentric video capture | Hardware with AI | Hardware / physical product | – | Hardware | 3 | 3 founders | |||
Nuclear-native autonomy software for hazardous inspections | – | – | – | Salem Robotics builds autonomy software for autonomous radiological surveys and inspections in hazardous nuclear environments. The platform coordinates mission planning, robot execution, radiation measurement, and auditable reporting across compatible robotic systems. The company says it has longsta | Industrials, Manufacturing and Robotics | Jon Xu sources: 1 | Robotics, AI Research, Security & Compliance Tools | Robotics | – | Hardware | Hardware | autonomous radiation surveys | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI security research lab for code vulnerabilities | United States | 1-10 | 2026 | Nebula Security describes itself as a security research lab that uses AI research and tooling to find vulnerabilities before attackers do. Its Vega product is an AI security research pipeline for real codebases, with reproducible, evidence-backed findings and reporting. The site shows active researc | B2B, Security | Ankit Gupta sources: 1 | Security & Compliance Tools, AI Research | – | AI-native service | DevTools | vulnerability detection | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||||
AI-powered tools for construction and logistics | United States | 1-10 | 2023 | Cosmic Robotics develops AI-powered equipment designed for construction and logistics in various environments. Their technology includes Particle AI for decision-making and adaptability, and the Constellation platform for project management and real-time insights. The company focuses on automating p | Industrials | Ankit Gupta sources: 1 | Robotics, Construction Robotics & Jobsite Automation, AI Research | Construction, Logistics, Robotics, Infrastructure | Hardware | Hardware | construction automation tools | Hardware with AI | Hardware / physical product | USD 8,000,000 | Hardware | 2 | 2 founders | |||||
Per-parcel disaster risk pricing models | United States | 1-10 | 2026 | Risklytics builds world models for disaster risk prediction. The company prices disaster risk per house or parcel rather than by ZIP code, using slope, fuel load, surge depth, soil, and construction factors. It is pre-launch and says it is backed by Combinator. | Fintech, Insurance | Ankit Gupta sources: 1 | Analytics & BI: Data analytics, Insurance tech | – | – | AI-native service | Fintech | property risk simulation | AI-native application | Software only | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
Bimanual home robots with remote teleoperation | United States | 1-10 | 2026 | NORI builds bimanual robots for home and office tasks, including autonomous household chores and remote teleoperation. The site highlights two models, NORI L2 and NORI L2 Grande, plus a skills marketplace for sharing trained robot skills. The company positions the robots for chores such as loading d | Industrials, Manufacturing and Robotics | Gustaf Alstromer sources: 1 | Robotics | Robotics | – | Hardware | Hardware | bimanual household robots | Hardware with AI | Hardware / physical product | – | Hardware | 1 | 1 founder | ||||
Rules-based S&P 500 trend investing | United States | 1-10 | 2026 | Ekpa is a pre-launch research-and-education product built around one daily rule for the S&P 500. It stays invested while the index trades above its long-term moving average and moves to cash when the trend breaks. The site emphasizes transparent signals, broker custody remaining with the user, and a | Fintech, Asset Management | Ankit Gupta sources: 1 | Investment Research, Investment Banking | – | – | Fintech | Fintech | trend-rule investing | Not primarily AI | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI government affairs firm | – | – | – | Justinian describes itself as the first AI government affairs firm. It combines lobbyists and AI agents for policy monitoring, lobbying execution, and opportunity capture. The company says it is backed by Y Combinator. | B2B | Vivian Midha Shen sources: 1 | Other | Analytics, Government, Fintech | – | AI-native service | Legal | regulatory monitoring tools | AI-native application | Software only | – | Services-as-software (AI-native service) | – | – | ||||
Forecasting physical automation and robot capability | – | – | – | Robocurve is a Public Benefit Corporation that studies physical AI and robot capabilities. It independently evaluates robots and the models that control them, then reports results for public understanding. The company frames its work around societal preparedness for the pace of robotic progress. | Industrials, Manufacturing and Robotics | Ankit Gupta sources: 1 | AI Research, Robotics, Other | Robotics | Hardware | Hardware | robot evaluation benchmarks | AI infrastructure / tooling | Hardware / physical product | – | Hardware | 2 | ||||||
Agentic post-sales intelligence platform | United States | 1-10 | 2026 | Amulet is an agentic platform for post-sales teams that turns tickets, calls, emails, and usage trends into account-level answers. It reads connected customer data, cites the underlying evidence, and supports actions from Slack or within its own interface. The product is backed by Y Combinator and i | B2B, Operations | Diana Hu sources: 1 | CRM Platforms, Sales Enablement Tools, Customer Support, Analytics & BI: Data analytics, Workflow automation | – | – | – | – | CRM & Sales | workflow automation tools | – | – | – | – | 2 | 2 founders | |||
AI-native research workspace for materials labs | – | – | – | 83 Sciences builds an intelligence engine and workspace for scientific research, with a stated emphasis on materials scientists. The platform captures experimental observations, structures research data, and supports later querying of a lab brain to review prior work. It also helps teams analyze fai | Industrials | Tyler Bosmeny sources: 1 | Analytics & BI: Data analytics, AI Research, Collaboration/Productivity | Analytics | – | AI-enhanced software | Manufacturing | materials research platform | AI-native application | Software only | – | Self-serve SaaS / software | 3 | 3 founders | ||||
AI processing unit for mortgage closing | United States | 1-10 | 2026 | Vestris builds software for mortgage title and closing workflows. Its agents log into tax portals, handle communications automatically, generate title abstracts, and issue title commitments. The company says it is backed by Y Combinator and is covering Washington, DC and Montgomery County, Maryland, | Real Estate and Construction, Housing and Real Estate | Jared Friedman sources: 1 | Workflow automation, HR Software, Other | – | AI-native service | Legal | mortgage workflow automation | AI-native application | Software only | – | Self-serve SaaS / software | – | – | |||||
Local-first workflow memory for AI agents | – | 1-10 | – | screenpipe captures what users see, say, and do, then turns that activity into searchable memory and automations. The product runs locally on macOS, Windows, and Linux, with open APIs and on-device privacy controls. It is positioned as workflow memory infrastructure for individuals and teams that wa | B2B, Productivity | Gustaf Alstromer sources: 1 | Workflow automation, Collaboration/Productivity, AI Research, Other | Analytics, Productivity | AI-enhanced software | DevTools | searchable screen recordings | AI-native application | Software only | – | Self-serve SaaS / software | 1 | 1 founder | |||||
AI knowledge layer for business teams | United States | 1-10 | 2026 | LemonLime describes itself as an AI knowledge layer that connects existing business tools and structures company data for AI use. The site says it learns how a business operates and deploys AI specialized for each team, with examples across marketing, sales, operations, support, and finance. It also | B2B | Diana Hu sources: 1 | AI Research, Workflow automation, Analytics & BI: Data analytics | Analytics, Fintech, Healthcare IT, Marketing, Operations, Productivity | AI-native service | DevTools | AI automation layer | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||||
Voice AI gateway with benchmark routing | United States | 1-10 | 2024 | Speko provides a voice-AI gateway that routes speech-to-text, language models, and text-to-speech through one API. Its platform adds automatic failover, live benchmarks, and voice-native retrieval for browser and phone agents. Y Combinator backed the company in S26, and the site says SOC 2 and HIPAA | B2B, Infrastructure | Tyler Bosmeny sources: 1 | AI Research, Cloud/DevOps Tools | – | – | Developer infrastructure | DevTools | voice AI gateway | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 1 | 1 founder | ||||
Agent commerce infrastructure for AI agents | – | – | – | Rindler is a translation layer between AI agents and the web. It exposes websites through a hosted MCP server that returns structured JSON, and it handles authentication, navigation, retries, and error recovery server-side. The company positions itself around deterministic access to commerce workflo | B2B, Infrastructure | Ankit Gupta sources: 1 | AI Research, Dev tools for AI Agents, Workflow automation | – | – | Developer infrastructure | DevTools | web API translation | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | ||||
Specialized AI agents for back-office work | – | – | – | Async builds specialized AI agents that automate administrative and operational work inside existing company systems. The site says it audits workflows, identifies automation opportunities, and deploys agents across tools like email, CRM, calendars, files, and document systems. It also presents SOC | B2B | Brad Flora sources: 1 | Workflow automation | Analytics, Operations, Productivity | AI-native service | DevTools | workflow automation agents | AI agent for a vertical | Software only | – | Services-as-software (AI-native service) | 2 | 2 founders | |||||
Runtime debugging layer for AI agents | United States | 1-10 | 2026 | Hyperprobe provides a runtime data layer for AI-native software, with an SDK and agent that capture production telemetry. It records live breakpoints, variable values, stack traces, and debugger state from running services without redeploying code. The site also shows a VS Code plugin, Model Context | B2B, Engineering, Product and Design | Brad Flora sources: 1 | Dev tools for AI Agents, Analytics & BI: Data analytics, Cloud/DevOps Tools | – | – | Developer infrastructure | DevTools | runtime telemetry agent | AI-native application | Software only | – | Developer platform / API / infra | 2 | 2 founders | ||||
Production conversation analysis for AI agents | – | – | – | Agnost AI continuously analyzes production conversations from chat and voice systems. It identifies where users get stuck, repeat retries, or fail to convert, then turns the highest-impact patterns into reviewed fixes for agents. The company says its product works with any LLM, any framework, and us | B2B, Analytics | Tyler Bosmeny sources: 1 | Customer Support, AI Research | – | AI-enhanced software | DevTools | conversation analytics | AI-native application | Software only | USD 500,000 | Self-serve SaaS / software | 2 | 2 founders | |||||
Medical device procurement optimization for independent surgery centers | United States | 1-10 | 2026 | Floracene shows independent surgery centers the best-priced equivalent implant for every procedure based on their manufacturer contracts. Over 90% of expensive implants used are clinically interchangeable, and switching to a clinically-equivalent device can recover 20-30% of that spend. The company | Healthcare | Harshita Arora sources: 1 | – | – | – | – | Marketplace | Health | implant cost optimization | AI-native application | Software only | – | Self-serve SaaS / software | 1 | 1 founder | |||
Biogas-to-chemicals modular reforming technology | – | – | – | Rise Reforming converts stranded biogas from wastewater plants, farms, and landfills into chemicals on site. The company says its patent-pending process produces dimethyl ether, methanol, and dimethyl carbonate through a three-step system. It reports more than 1,800 hours of stable syngas production | Industrials, Climate | Jared Friedman sources: 1 | Clean Power Software Platforms, Sustainable Fuels & Alternative Energy, Carbon Capture & Emissions Reduction Tech | – | – | Biotech | Manufacturing | biogas conversion technology | Not primarily AI | Hardware / physical product | – | – | 3 | |||||
AI-native ERP implementation platform | United States | 1-10 | – | Trope builds an AI-native platform for ERP partners handling implementations, migrations, and post go-live optimization. Its agents review meetings, requirements, configurations, data, and code, then flag mismatches with evidence and can make fixes automatically. The company says ERP teams spend $50 | B2B | Jon Xu sources: 1 | AI Research, Workflow automation | Analytics, Fintech, Operations, Productivity, Engineering | AI-native service | DevTools | ERP optimization platform | AI-native application | Software only | USD 125,000 | Self-serve SaaS / software | 2 | 2 founders | |||||
Local-first inference router for AI models | United States | 1-10 | 2025 | Conifer is an inference gateway and model router that sends each query to the cheapest model that can handle it. The product starts with free models on the user’s own hardware, and it supports GPU-accelerated local inference with custom Metal and CUDA kernels. The site also positions Conifer as a un | B2B | Gustaf Alstromer sources: 1 | AI Research, Dev tools for AI Agents, Cloud/DevOps Tools, Workflow automation | – | Developer infrastructure | DevTools | inference gateway | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | |||||
Defense robotics for situational awareness | – | – | – | Earendil Robotics builds defense robotics and vision systems for tactical users. Its product line includes soldier situational awareness hardware, an autonomous interceptor drone, and an ultra-lightweight tactical sight. The company says it is backed by Y Combinator. | Industrials, Defense | Vivian Midha Shen sources: 1 | Robotics, AI Research | Manufacturing | – | Hardware | Hardware | tactical situational awareness | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
Distributed GPU cloud for inference | – | – | – | OpenRelay runs production inference across a distributed network of GPUs. It positions itself as a resilient compute layer for AI applications and describes the system as the CDN of inference. The platform combines GPU rental, hosted inference, and provider participation across a fault-tolerant mesh | B2B, Engineering, Product and Design | Brad Flora sources: 1 | Cloud/DevOps Tools, AI Research, Analytics & BI: Data analytics | – | – | Developer infrastructure | DevTools | distributed GPU inference | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | ||||
AI-powered flight planning for aviation professionals | United States | 1-10 | 2023 | Skymerse delivers AI-driven flight planning that reduces preparation time from hours to minutes. Its Flight AI Agent processes NOTAMs, weather, and traffic data to provide real-time route optimization and safety predictions. The platform integrates with existing electronic flight bags and supports V | Industrials, Aviation and Space | – | AI Research, Cloud/DevOps Tools, Other | – | – | AI-native service | Hardware | flight planning automation | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 1 | 1 founder | ||||
Domestic PCB assembly with X-ray verification | United States | 1-10 | – | ProvenMetal provides domestic fast-turn PCB assembly for hardware, robotics, and defense teams. The site highlights seven-day standard turnaround, instant quoting, and X-ray verification for every board. It also says the company ships inspection proof and data with orders, and it is backed by Combin | Industrials, Manufacturing and Robotics | Vivian Midha Shen sources: 1 | Manufacturing, Other | Robotics | – | Hardware | Hardware | fast-turn PCB assembly | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
AI-native document intelligence for construction | United States | 1-10 | – | Alloovium presents itself as an AI for construction and engineering professionals. The product is a document intelligence workplace that handles questions, recurring reporting, site voice capture, version control, and compliance tracking across project documents. It says it is deploying across 400 m | Real Estate and Construction, Construction | Gustaf Alstromer sources: 1 | Other | Construction, Engineering | – | AI-enhanced software | Manufacturing | document intelligence | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Frontier computer-use agents for enterprise workflows | United States | 1-10 | 2026 | Zomma builds frontier computer-use agents that run inside secure cloud computers. The product operates across browsers, files, spreadsheets, PDFs, and desktop applications while a human team watches, guides, corrects, and can take over. The company describes itself as an applied AI lab bringing fron | B2B | Brad Flora sources: 1 | AI Research, Dev tools for AI Agents, Workflow automation | – | AI-native service | Fintech | back-office automation | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 3 | ||||||
Swipeable market research, backed by Y Combinator | United States | 1-10 | 2026 | OpenTrade presents itself as a swipeable market-research product centered on one-call daily prompts and three widely debated stories. The site says users can chat with an OpenTrade card that compresses numbers, charts, and filings into a single swipeable view. Its legal page describes the site as a | Consumer | Diana Hu sources: 1 | Analytics & BI: Data analytics, Other | Fintech | – | Fintech | Fintech | market research cards | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Engineering intelligence for capital projects | – | – | – | Torus provides AI agents for capital projects that read P and IDs, HMBs, spec sheets, and related engineering documents. The system cross-references parameters across documents, flags mismatches, and produces provenance-backed outputs for review. The site says the product can be deployed as Torus Ma | Industrials | Gustaf Alstromer sources: 1 | AI Research, Workflow automation | Analytics, Engineering, Fintech | AI-enhanced software | Manufacturing | engineering document analysis | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||||
AI technical interview pipelines from code | United States | 1-10 | 2025 | Litmus generates technical interview pipelines from repositories, tickets, and job descriptions. It produces assessments and candidate workflows around the work a team is actually shipping. The company says it is backed by Y Combinator. | B2B, Recruiting and Talent | Jared Friedman sources: 1 | Recruiting Software, HR Software | – | – | AI-enhanced software | DevTools | technical interview pipelines | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Y Combinator-backed solar installation robots | – | 11-50 | – | Libra Robotics is a Silicon Valley startup building AI-powered autonomous robots for large-scale solar installation. The company offers Robot-as-a-Service pricing and remote monitoring for utility-scale solar deployment. Its system combines computer vision, automated fastening, and automation-ready | Industrials, Energy | Tyler Bosmeny sources: 1 | Robotics, AI Research, Clean Power Software Platforms | Robotics | – | Hardware | Hardware | solar installation robots | Hardware with AI | Hardware / physical product | – | Hardware | – | – | ||||
Secure research brain for R&D teams | – | – | – | Osseus connects existing research tools into a permissioned research brain for R&D teams. The platform combines permission-aware chat, background automations, and proactive watcher alerts across connected systems. It is backed by Y Combinator and advertises SOC 2, ISO 27001, HIPAA, and GDPR availabi | B2B, Productivity | Jared Friedman sources: 1 | Collaboration/Productivity, Analytics & BI: Data analytics, Workflow automation | Automotive, Robotics | – | AI-enhanced software | Health | secure research platform | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Data engineering agent with lineage | United States | 1-10 | 2026 | Alkera builds a data engineering agent that works across the data stack with governance, lineage, and a living knowledge base. It can modify queries, transformations, and models while tracking exact column-level lineage and keeping changes within access and policy rules. The product runs in the comm | B2B, Engineering, Product and Design | Ankit Gupta sources: 1 | Analytics & BI: Data analytics, Cloud/DevOps Tools, Workflow automation | Analytics | Developer infrastructure | DevTools | data governance agent | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 3 | 3 founders | |||||
Production trace tuning for specialist open models | United States | 1-10 | 2026 | Understudy turns production traces and expert review into specialized open models that teams own. The company organizes its workflow around capture, evaluate, train, and deploy steps for repeated LLM tasks. It emphasizes tuning the harness, model, and supply path for workloads with cost, latency, an | B2B, Infrastructure | Tyler Bosmeny sources: 1 | AI Research, Dev tools for AI Agents | – | – | Developer infrastructure | DevTools | open model training | AI infrastructure / tooling | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Interactive multimodal generation platform | – | 1-10 | 2026 | Palette is a creative engine for video and multimodal content that generates, edits, and directs material on one canvas. The product includes Generate, Edit, Direct, Characters, Models, and Studio, plus workflow features for brand kits, storyboard-to-sequence creation, real-time collaboration, perfo | B2B | Ankit Gupta sources: 1 | Other | – | – | AI-enhanced software | Consumer | multimodal content creation | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Open-source credential gateway for AI agents | – | 1-10 | – | OneCLI is an open-source gateway, encrypted vault, and dashboard packaged in a single Docker container. It routes agent requests through OneCLI while keeping service keys inside the vault. The company says it is backed by Y Combinator and developed openly on GitHub. | B2B, Security | Brad Flora sources: 1 | Security & Compliance Tools, Cloud/DevOps Tools, Workflow automation | Security | Developer infrastructure | DevTools | credential management gateway | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | |||||
AI agents evaluated in real business workflows | France | – | 2024 | Ooak Data evaluates AI agents in real-world business environments, focusing on unstructured and multi-modal contexts. Their platform allows for performance assessment across various business tools and workflows, utilizing curated datasets for training. The company aims to bridge the gap between AI p | B2B | Diana Hu sources: 1 | AI Research, Dev tools for AI Agents, Analytics & BI: Data analytics | – | – | Developer infrastructure | DevTools | RL environment builder | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | ||||
Keyboard-driven dashboard for coding agents | United States | 1-10 | 2026 | Hoplite describes itself as a fast, keyboard-driven dashboard for coding agents. The homepage does not reveal additional modules, integrations, or technical details beyond that description. No public traction signals, customers, funding, or partnerships were visible on the site. | Fintech, Consumer Finance | Vivian Midha Shen sources: 1 | Collaboration/Productivity, Dev tools for AI Agents | Analytics, B2B, Consumer, Engineering, Fintech, Human Resources, Operations, Productivity | – | Developer infrastructure | DevTools | AI agent frameworks | AI infrastructure / tooling | – | – | Developer platform / API / infra | 2 | 2 founders | ||||
Enterprise IT agents for system changes | United States | 1-10 | – | Assemble deploys long-running agents that perform development work inside enterprise systems. The platform scopes dependencies, modifies logic, and validates changes across connected business applications. It is aimed at enterprise IT teams managing changes across systems such as Salesforce, NetSuit | B2B | Ankit Gupta sources: 1 | Dev tools for AI Agents, Workflow automation, Cloud/DevOps Tools | – | – | Developer infrastructure | DevTools | development automation agents | AI agent for a vertical | Software only | – | Developer platform / API / infra | 3 | |||||
Agent-native chip design toolchain | United States | 1-10 | 2026 | hardware intelligence builds the end-to-end, agent-native toolchain for chip design. Its first product, Wave, is an agentic waveform debugger that runs in the terminal and launched in July 2026. The company says it is backed by Y Combinator. | B2B, Engineering, Product and Design | Jon Xu sources: 1 | Other | – | – | Hardware | Hardware | waveform debugger | Hardware with AI | Hardware / physical product | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AR mapping for underground utilities | United States | 1-10 | 2026 | SubVysion builds AI-powered augmented-reality maps of underground infrastructure. The company combines multi-sensor GPR and 3D survey data, then aligns and validates it into a single georeferenced ground truth. Users can view underground utilities on-site through a mobile AR app. | Real Estate and Construction, Construction | Gustaf Alstromer sources: 1 | Analytics & BI: Data analytics, AI Research, Other | Construction, Engineering | – | Hardware | Manufacturing | underground utility mapping | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
Live alerts for anything happening worldwide | United States | 1-10 | 2026 | Notyfi tracks events, signals, and updates across the web, then delivers alerts as soon as they appear. The product exposes notifications through email, a live dashboard, an API, and MCP, and it is built for AI agents and workflows. Y Combinator lists the company as active in its Summer 2026 batch, | B2B | Jared Friedman sources: 1 | Other | – | – | AI-enhanced software | Other | event tracking alerts | AI infrastructure / tooling | Software only | – | Self-serve SaaS / software | – | – | ||||
AI personal health and longevity companion | United States | 1-10 | 2026 | Illume Labs builds a pre-release consumer app that gathers health, fitness, wearable, lab, CGM, genome, and profile data in one place. The company describes the product as a wellness and longevity tool, not a medical device, and says it generates personalized insights and analysis from connected and | Healthcare, Consumer Health and Wellness | Ankit Gupta sources: 1 | Health Data Integration & Interoperability Platforms, Analytics & BI: Data analytics | Healthcare | Consumer | Consumer | health data aggregator | AI-native application | Software only | – | Consumer app | 3 | 3 founders | |||||
AI-powered context layer for customer data | United States | 11-50 | 2024 | Nex unifies real-time unstructured and structured customer data and conversations from various sources into an intelligent context layer. The platform features AI-powered APIs that allow access to this context from anywhere, facilitating seamless data synchronization across systems. | B2B, Productivity | Gustaf Alstromer sources: 1 | CRM Platforms, Sales Enablement Tools, Analytics & BI: Data analytics, Marketing & Advertising Tech | – | – | AI-native service | CRM & Sales | intelligent context layer | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI coworkers for accounting teams | United States | 1-10 | 2026 | Rational builds AI coworkers for accounting and finance teams that handle recurring AP, close, reconciliation, and document follow-up work. The system prepares packets, routes exceptions, stops for human judgment, and keeps decision history tied to the source and recommendation. It is backed by Y Co | B2B, Operations | Jared Friedman sources: 1 | AI Research, Accounting Tech, Workflow automation | – | – | AI-enhanced software | Fintech | AP automation agent | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Robotics fleet teleoperation and data collection | United States | 1-10 | 2026 | AKTORIA Robotics provides remote data collection, fleet management, and teleoperation for deployed robots. The homepage describes 24-hour remote data capture and monitoring for robot fleets, with a train, deploy, and monitor workflow. No public customer list, funding amount, or named investors were | Industrials, Manufacturing and Robotics | Diana Hu sources: 1 | Robotics, AI Research, Fleet Management & Route Optimization Software | Robotics | – | – | Hardware | Hardware | remote fleet management | Hardware with AI | Hardware / physical product | – | Services-as-software (AI-native service) | 2 | 2 founders | |||
Multiplayer AI game maker for browser games | United States | 1-10 | 2026 | Instaplay is a web-based AI game maker that turns text prompts into playable browser games. The product generates code, art, and rules for party, co-op, competitive, local, and online multiplayer games. The site positions the output as shareable web links and remixable examples rather than a traditi | Consumer, Gaming | Diana Hu sources: 1 | AI Game Development Platforms | – | – | AI-native service | Consumer | text-to-game generator | AI-native application | Software only | – | Self-serve SaaS / software | 3 | 3 founders | ||||
Operating layer for boutique hotels | – | – | – | Axelrod runs daily hotel and resort operations inside existing systems and teams. It coordinates work across guests, rooms, rates, access, maintenance, supplies, owner reporting, PMS, channels, pricing, messaging, and accounting. The company says it powers Michelin Key awarded properties and Marriot | B2B | Brad Flora sources: 1 | Other | Analytics | – | AI-native service | Blue Collar SaaS | hotel operations platform | AI-native application | Software only | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
AI-native hardware R&D platform for engineers | United States | 1-10 | 2025 | DAQstra provides an AI-native platform that unifies sensors, control systems, and cloud analytics for hardware R&D. It delivers real-time performance and automated testing at scale. The platform is designed for engineers in aerospace, automotive, and academia. | B2B | Gustaf Alstromer sources: 1 | AI Research, Cloud/DevOps Tools, Analytics & BI: Data analytics | Automotive, Robotics | – | Hardware | Hardware | hardware analytics platform | AI-native application | Hardware / physical product | – | Developer platform / API / infra | 2 | 2 founders Anchit Kumar | ||||
Living wiki for codebase context | United States | 1-10 | 2025 | Almanac is a living wiki for codebases that captures engineering context as developers work. The product reads completed coding sessions and rewrites affected documentation pages, while citing the source material for agents and teammates. It appears built for teams using coding agents such as Claude | B2B | Harshita Arora sources: 1 | Collaboration/Productivity, Other | – | Developer infrastructure | DevTools | codebase wiki | AI-native application | Software only | – | Developer platform / API / infra | 3 | 3 founders | |||||
AI operations for regulated finance | – | 1-10 | – | Rapidfolio is an AI operations platform for regulated industries, with a primary emphasis on compliance, operations, and fraud workflows. It automates manual financial reviews with human-level accuracy, full auditability, and built-in security controls. The company says it serves compliance and oper | B2B | Gustaf Alstromer sources: 1 | AI Research, Compliance Tech, Workflow automation | Analytics, Fintech, Operations | – | Fintech | Fintech | compliance automation | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Voice AI for automating accounts receivable collections | United States | 11-50 | – | Billow AI specializes in automating accounts receivable collections using voice AI technology. Their approach reduces collection times significantly while maintaining customer relationships. This results in improved cash flow and faster recovery of outstanding payments for businesses. | B2B, Finance and Accounting | – | Payments & FinOps Platforms, AI Research, Workflow automation | – | – | AI-native service | Fintech | payments automation | AI-native application | – | – | Services-as-software (AI-native service) | 1 | 1 founder | ||||
Operating system for physical goods companies | United States | 1-10 | 2026 | Bizmark is the operating system for companies that make, move, or sell physical goods. It connects a company's existing systems, spreadsheets, and institutional knowledge to generate optimized decisions and automated workflows. The platform adapts to each company's operations and can deliver a worki | B2B | Jon Xu sources: 1 | Workflow automation, Supply Chain Visibility & Tracking Tools, Analytics & BI: Data analytics, Collaboration/Productivity | Manufacturing, Logistics | – | AI-enhanced software | Manufacturing | operational optimization software | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Autonomous private AI for custom model training | United States | 1-10 | 2026 | Belvedir offers an autonomous platform that trains custom AI models and memory systems using a mix of weight and memory updates, hosts them privately, and continuously improves them in production. It replaces expensive forward-deployed engineering previously only accessible to large enterprises with | B2B | Harshita Arora sources: 1 | AI Research, Dev tools for AI Agents | – | – | AI-native service | DevTools | custom AI training | AI-native application | Software only | – | Self-serve SaaS / software | 1 | 1 founder | ||||
Factory-direct supply for US importers | – | – | – | Donkey describes itself as a modern trading company for US importers. The homepage says buyers can send one photo, identify the factory that actually makes a product, and receive a delivered USD quote within 72 hours. It combines supplier identification, landed pricing, inspections, customs handling | B2B, Supply Chain and Logistics | Harshita Arora sources: 1 | Supply Chain Visibility & Tracking Tools, Procurement & Supplier Management Platforms, Payments & FinOps Platforms | B2B, Supply Chain, Logistics | – | Marketplace | Manufacturing | factory sourcing platform | Not primarily AI | Software only | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
Open-source customization layer for SaaS products | United States | 1-10 | 2026 | Vendo embeds an agent inside a product that lets every customer build their own features, automations, and micro-apps in plain English. It learns the product's theme, components, and API so users can describe what they need and get it built live, never exceeding the product's existing guardrails. Ba | B2B, Engineering, Product and Design | Ankit Gupta sources: 1 | AI Research, Dev tools for AI Agents, Workflow automation, Collaboration/Productivity | – | Developer infrastructure | DevTools | customizable automation agent | AI agent for a vertical | Software only | – | Developer platform / API / infra | 2 | 2 founders | |||||
AI-powered automated drawing review for manufacturers | United States | 1-10 | 2026 | Hera automates design review for mechanical drawings by checking GD&T conformance against ASME Y14.5-2018, code compliance against ASME BPVC/B31/AWS, tolerance stacks across sheets and interfaces, and drawing integrity for datums and contradictions. Backed by Y Combinator (Summer 2026), it reduces m | Industrials | Diana Hu sources: 1 | Manufacturing, AI Research, Workflow automation | Manufacturing, Engineering, Automotive, Analytics | – | AI-enhanced software | Manufacturing | automated drawing review | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI agents for field service shops | – | – | – | Kebra presents itself as an AI native operating layer for field service companies. Its product turns technician job recordings into structured records, then routes warranty claims, invoices, customer updates, and parts orders into existing tools. The site frames the company around shop operations fo | B2B, Operations | Jared Friedman sources: 1 | Workflow automation, AI Research | Analytics | – | AI-native service | Blue Collar SaaS | report automation | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Autonomous AI Scientists for research | – | – | – | rekursiv.ai builds autonomous systems of models that hypothesize, design experiments, run tests, and interpret results like research scientists. The company says its AI Scientists have already discovered new machine learning methods and algorithms that beat state of the art on several benchmarked pr | B2B, Productivity | Jared Friedman sources: 1 | AI Research, Dev tools for AI Agents | Analytics | AI research | DevTools | autonomous research systems | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||||
Agent-native AI accounting firm for Finnish SMBs | United States | 1-10 | 2026 | Last Accounting Company (LAC) is a full-stack AI accounting firm that replaces traditional accounting firms and software with one fixed-price service. It uses AI agents to handle bookkeeping, tax filings, and financial reporting, with a certified accountant signing off on the work. LAC has processed | B2B, Finance and Accounting | Gustaf Alstromer sources: 1 | Accounting Tech, AI Research, Workflow automation | Accounting | – | AI-native service | Fintech | automated bookkeeping | AI-native application | Software only | – | Services-as-software (AI-native service) | 4 | |||||
Weekly GPU hour marketplace with instant liquidity | United States | 1-10 | – | Computable operates a marketplace to buy, sell, and redeem NVIDIA H100 GPU hours for specific calendar weeks, applying commodity trading mechanics to GPU compute. Founders, who built trading infrastructure at Jump Trading and Coinbase, draw parallels between today's compute markets and energy market | Fintech | Brad Flora sources: 1 | Cloud/DevOps Tools, AI Research, Analytics & BI: Data analytics | – | – | – | Marketplace | DevTools | GPU hour marketplace | AI infrastructure / tooling | Software only | – | Marketplace | 2 | 2 founders | |||
AI planning and scheduling for complex manufacturing | United Kingdom | 1-10 | 2026 | Orvixo builds AI planning and scheduling that models a factory's unique rules, constraints, and priorities to generate optimal production schedules. Its system connects to existing ERP systems, machines, and frontline data to continuously monitor operations and instantly replan when disruptions such | Industrials, Manufacturing and Robotics | Jon Xu sources: 1 | AI Research, Workflow automation, Manufacturing | Manufacturing | – | AI-enhanced software | Manufacturing | AI scheduling engine | AI-native application | Software only | – | Self-serve SaaS / software | 1 | 1 founder | ||||
Autonomous warehouse robots for pick operations | – | – | – | Manifold Industries builds autonomous warehouse robots for case picking, trailer loading, unloading, and palletizing. The system combines warehouse robots with orchestration software that connects to ERP, WMS, and WES workflows, plus remote supervision for exception handling. The site says deploymen | Industrials, Manufacturing and Robotics | Jon Xu sources: 1 | Robotics, AI Research | Robotics, Logistics, Supply Chain | – | Hardware | Hardware | autonomous warehouse robots | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
External risk intelligence for margins | – | – | – | Shielded connects internal business data with external events, prices, and regulatory changes. The platform maps how outside signals affect margins, exposure, and operational decisions, then recommends actions proactively. The website shows a finance and supply chain risk product with scenario model | B2B, Finance and Accounting | Jared Friedman sources: 1 | Analytics & BI: Data analytics, HR Software, Other | Finance | – | – | Fintech | Fintech | risk management platform | AI-native application | Software only | – | Self-serve SaaS / software | – | – | |||
AI social games and benchmark arenas | – | – | – | Olam Labs builds multiplayer simulation games where humans and AI agents compete in structured social environments. Its products include Social Arena, Social Poker, Warpath, Tradewinds, Market Rush, and Tokenshire, plus internal multi-agent simulations for research. The company positions these syste | B2B | Harshita Arora sources: 1 | AI Research | Analytics, Social | – | AI research | DevTools | multiplayer AI simulations | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
RL environments for training AI on industrial operations | United States | 1-10 | 2026 | Maingen builds reinforcement learning environments for industrial operations, targeting a $5 trillion slice of the US economy so frontier labs can train models that run factories. Its first product, SolarBench, benchmarks AI agents on a simulated solar farm remote operations desk using scenarios der | Industrials, Energy | Harshita Arora sources: 1 | AI Research, Cloud/DevOps Tools, Analytics & BI: Data analytics, Workflow automation | Analytics, Consumer, Engineering, Fintech, Healthcare IT, Manufacturing, Robotics, Supply Chain, Logistics | – | AI research | Manufacturing | solar farm benchmarking | AI infrastructure / tooling | Software only | – | Self-serve SaaS / software | 1 | 1 founder | ||||
Portable personal memory layer for AI apps | United States | 1-10 | 2026 | Egoist Machines builds the EGOIST AI Passport, a personal context layer that carries users' preferences, history, and identity across AI applications like ChatGPT and Claude. Users create a living profile of taste, preferences, and interests using one-click connectors across hundreds of apps, and ch | Consumer | Harshita Arora sources: 1 | AI Research, Customer Support, Other | – | AI-enhanced software | Consumer | personal context layer | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||||
Autonomous robots for data center lifecycle tasks | United States | 1-10 | 2026 | Proprio Robotics builds physical AI models and custom hardware that give robots the dexterity to perform the full lifecycle of data center infrastructure work — assembly, maintenance, and decommissioning of servers. The robots handle tasks such as racking and unracking servers, inserting fans, extra | Industrials, Manufacturing and Robotics | Ankit Gupta sources: 1 | Robotics, AI Research | Robotics | – | Hardware | Hardware | data center robotics | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
Personalized mRNA cancer vaccines for dogs | United States | 1-10 | 2026 | Gamgee is building an end-to-end platform for personalized mRNA cancer vaccines for dogs. The company sequences a dog's tumor and healthy DNA, identifies mutations unique to its cancer, and designs a vaccine that teaches the immune system what to attack, managing the entire process from vet intake a | Healthcare, Drug Discovery and Delivery | Tyler Bosmeny sources: 1 | Other | Healthcare, Therapeutics, Drug Discovery | – | – | Biotech | Health | personalized mRNA vaccines | Not primarily AI | Hardware / physical product | – | Services-as-software (AI-native service) | – | – | |||
AI agents for computer automation | – | 1-10 | 2025 | Induction Labs builds advanced foundation models that operate on computers and the real world. Their unique approach focuses on learning from human behavior data at scale, utilizing the largest dataset of computer interactions ever collected. This enables their models to execute tasks autonomously w | B2B, Infrastructure | Harj Taggar sources: 1 | AI Research, Dev tools for AI Agents | – | AI-native service | DevTools | autonomous foundation models | Foundation model / frontier research | Software only | – | Developer platform / API / infra | 2 | 2 founders | |||||
AI system that replaces IT consultancies | Sweden | 1-10 | 2026 | Blaise is an AI system that scopes, builds and deploys custom enterprise software end-to-end, performing the work of an entire human IT consultancy in days at a fraction of the cost. It is already deployed with select governments and enterprise partners. Blaise is developed by Swedish Superintellige | B2B | Harshita Arora sources: 1 | AI Research, Dev tools for AI Agents, Workflow automation, Other | – | – | AI-enhanced software | DevTools | custom enterprise software | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Operational intelligence for radiology networks | United States | 11-50 | 2026 | Avoca Systems provides operational intelligence for radiology networks, with tools spanning booking, patient experience, and clinic operations. The company says it covers the full patient journey, including calls, self-service booking, eReferrals, reminders, prep, results delivery, and follow-up sca | Healthcare | Jon Xu sources: 1 | Healthcare Operations & Revenue Cycle Management, CRM Platforms | – | – | AI-enhanced software | Health | radiology booking engine | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Applied AI for government affairs | – | – | – | Locke is an applied AI company that says it changes how companies and governments work together. Its first product, Locke Government Affairs, is an AI-native government affairs firm for tracking regulations, lobbying policymakers, and winning government contracts. The site says the team draws from T | B2B | Vivian Midha Shen sources: 1 | AI Research, Compliance Tech | – | – | – | AI-native service | Legal | government relations platform | AI-native application | Software only | – | Services-as-software (AI-native service) | 1 | 1 founder | |||
Maritime planned maintenance tracker for ship managers | United States | 1-10 | – | Derya AI provides a specialized software solution for maritime vessel maintenance planning. The platform enables ship managers to track planned maintenance tasks, attach supporting documents, and receive real-time notifications. It is designed specifically for maritime operations with a focus on red | B2B, Supply Chain and Logistics | Jared Friedman sources: 1 | Other | – | – | AI-native service | Manufacturing | – | AI-native application | – | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
iOS app development with 4.5-star average rating | United States | 1-10 | 2006 | Neuron Industries develops iOS apps for iPhone and iPad. Their apps receive an average 4.5-star rating in app stores. The company is based in Santa Monica, California. | Industrials, Manufacturing and Robotics | – | Other | – | – | AI-enhanced software | Manufacturing | iOS app development | AI-native application | Software only | – | Self-serve SaaS / software | – | – | ||||
Real-time 3D configurator and AI upsells for hospitality event booking | – | 1-10 | – | Zaplar provides a B2B SaaS platform for hotels and venues to manage event bookings through a real-time 3D room configurator, automated quotes and contracts, and AI-driven upsell suggestions. The platform offers a tailored guest portal and seamless integration with existing CRM, PMS, and payment syst | B2B, Operations | Jared Friedman sources: 1 | Other | – | – | AI-enhanced software | Blue Collar SaaS | event management software | AI-native application | Software only | – | Self-serve SaaS / software | 4 | |||||
Reliable infrastructure to build, deploy, and manage real-world robots | United States | 1-10 | 2026 | Agency Tool Company gives robotics teams reliable infrastructure to build, deploy, manage, and operate real-world robots. Its two products are ATC Deploy, an over-the-air software delivery and fleet-management system purpose-built for robotics, and ATC Build, a CI runner backed by hosted embedded co | Industrials, Manufacturing and Robotics | Harshita Arora sources: 1 | Robotics, Cloud/DevOps Tools, Software Testing & QA Automation Tools | Robotics | Hardware | Hardware | robotics fleet management | Hardware with AI | Hardware / physical product | – | Developer platform / API / infra | 2 | 2 founders | |||||
LLM agents that control robots | United States | 1-10 | 2025 | Waddle Labs provides an API that connects to robot arms and uses LLM agents to write control code from natural-language prompts. Its agents decompose goals into subtasks, write executable programs, call vision-language-action models, and verify outcomes, creating a working policy in approximately 20 | Industrials, Manufacturing and Robotics | Ankit Gupta sources: 1 | Robotics, AI Research, Dev tools for AI Agents | Robotics | – | Hardware | Hardware | robot control API | AI agent for a vertical | Hardware / physical product | – | Developer platform / API / infra | 2 | 2 founders | ||||
Floating nuclear-powered data centers at sea | United States | 1-10 | 2026 | Atomarine builds floating data center platforms on standardized barges produced in shipyards, anchored 10-12 nautical miles offshore. Each platform generates 75-100 MW of power on site starting with natural gas and transitioning to marine nuclear reactors, using a closed seawater cooling loop with a | Industrials, Energy | Tyler Bosmeny sources: 1 | Cloud/DevOps Tools, AI Research | – | – | Hardware | Hardware | floating data centers | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
At-home multispectral skin tracker with AI companion | United States | 1-10 | 2026 | Lumeria builds the Lumoscope, a multi-spectrum imaging device that clips to any phone and captures skin images using RGB, UV (365nm), and polarized light. The device measures hydration, redness, hyperpigmentation, sebum, texture, surface topography, lesion size, and distribution, while the Dermbot A | Healthcare, Consumer Health and Wellness | Tyler Bosmeny sources: 1 | Other | Healthcare, Consumer Electronics | – | Consumer | Consumer | multi-spectrum skin imaging | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
Private browser poker with instant cashouts | – | – | – | PokerClubHub is a browser-based private poker platform for playing in invite-only clubs without downloads. It supports No Limit Texas Hold'em, PLO 4, PLO 5, and PLO 6, and advertises deposits, withdrawals, and instant cashout. The site says it operates under an Anjouan gaming license, uses BMM Testl | Consumer, Gaming | Ankit Gupta sources: 1 | Other | – | – | – | Marketplace | Consumer | private poker platform | Not primarily AI | Software only | – | Marketplace | – | – | |||
On-device AI security for device fleets | – | – | – | Traceforce is an AI security and control platform for devices, with visibility across browser AI, desktop apps, and CLI agents. It monitors AI apps, MCPs, and CLI agents, and includes automated remediation plus real-time threat blocking. The site says it is trusted by companies that power the Fortun | B2B, Security | Brad Flora sources: 1 | Security & Compliance Tools, AI Research | – | AI-native service | DevTools | on-device AI security | AI-native application | Software only | – | Self-serve SaaS / software | 1 | 1 founder | |||||
Personalized AI learning app for any topic | United Kingdom | 11-50 | 2020 | Wondering is a learning app that turns any user-selected topic into a structured course. The homepage describes short, three-minute lessons, visual explanations, practice questions, and personalized learning preferences. It also offers guided learning paths and customization by goal, time commitment | Consumer | Diana Hu sources: 1 | Education Tech | Education | – | Consumer | Consumer | personalized learning courses | AI-native application | Software only | – | Consumer app | – | – | ||||
Open-source knowledge graph for AI coding assistants | United Kingdom | 1-10 | 2026 | Graphify turns codebases, docs, SQL schemas, configs, and PDFs into an on-device knowledge graph that AI coding assistants can query instead of grepping through files. It is licensed under Apache 2.0, supports 36 programming languages and 17 AI coding assistants, and requires no account or telemetry | B2B, Engineering, Product and Design | Jared Friedman sources: 1 | AI Research, Dev tools for AI Agents, Analytics & BI: Data analytics, Collaboration/Productivity | – | Developer infrastructure | DevTools | knowledge graph engine | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 1 | 1 founder | |||||
On-sensor AI image sensor lab | – | – | – | Synapse Semiconductor describes itself as a frontier semiconductor research lab building senses for physical AI. It builds image sensors that process AI on the sensor itself, replacing separate camera and GPU hardware with one chip. The site positions the product for edge vision systems that must pe | Industrials | Tyler Bosmeny sources: 1 | AI Research, Robotics, Other | Robotics | – | Hardware | Hardware | AI image sensors | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
Science-backed personalised probiotics with 1000+ strains | Australia | 1-10 | 2025 | gutgutgoose offers custom probiotic formulations based on microbiome testing. Their approach uses hospital-grade at-home tests and advanced sequencing to create tailored synbiotic blends. Clinical trials show 51.2% reduction in IBS severity and 2x increase in beneficial bacteria after 90 days. | Healthcare | Tyler Bosmeny sources: 1 | – | Healthcare, Healthcare IT, Consumer, Consumer Finance, Fintech, Therapeutics, Drug Discovery, Education, Analytics | – | Biotech | Health | personalized probiotics | Not primarily AI | Software only | USD 500,000 | Self-serve SaaS / software | 2 | 2 founders | ||||
Radio-wave camera seeing through walls with millimeter accuracy | United States | 1-10 | 2026 | Applied Electrodynamics builds WaveSight, a radio-wave imaging camera that sees through walls and maps mechanical, electrical, and plumbing systems with millimeter-level accuracy, producing a point cloud output accurate to 1 millimeter. The team previously co-invented the iPhone touchscreen and Nest | Industrials | Jon Xu sources: 1 | Other | Construction, Security | – | Hardware | Hardware | radio-wave imaging camera | Hardware with AI | Hardware / physical product | – | Hardware | 4 | |||||
YC-backed AI coordination research lab | – | – | – | Tracer is a YC-backed research lab that studies coordinated intelligence for AI systems. The company turns that research into products that aim to improve performance per token through intelligence allocation and coordination. Its latest product, Echo, exposes one OpenAI-compatible endpoint for chat | B2B | Diana Hu sources: 1 | AI Research, Dev tools for AI Agents | – | – | Developer infrastructure | DevTools | adaptive AI endpoint | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 1 | 1 founder | ||||
AI contract review for enterprise legal teams | – | – | – | Dock appears to be a contract review product for legal and business teams, presented under the Dock brand at trydock.ai. The company’s public site content was not fully retrievable in this run, so detailed product mechanics, customer references, and quantified results could not be verified. No relia | B2B | Brad Flora sources: 1 | Legal Tech, Workflow automation | – | – | – | AI-enhanced software | Legal | contract review automation | AI-native application | Software only | USD 6,500,000 | Self-serve SaaS / software | 1 | 1 founder | |||
Physical AI grippers for waste sorting | – | – | – | Grip Robotics builds physical AI grippers for waste management and material handling. The company says its grippers perceive, adapt, and manipulate objects with human-hand dexterity. Its website frames the product around automating dirty, dangerous, and repetitive work in the waste stream. | Industrials, Manufacturing and Robotics | Jared Friedman sources: 1 | Robotics, AI Research | Robotics | – | Hardware | Hardware | robotic grippers | Hardware with AI | Hardware / physical product | – | Hardware | 1 | 1 founder | ||||
Patient-data intelligence layer for EHR access | – | – | – | Hubble describes itself as the intelligence layer for patient information. It connects to EHRs, payers, and patient records through APIs, browser, and voice, and returns a single record with source attribution. The company says it is live in production, with 40+ tools live and audit logging on every | Healthcare, Healthcare IT | Jon Xu sources: 1 | Healthcare Operations & Revenue Cycle Management, Health Data Integration & Interoperability Platforms, Analytics & BI: Data analytics | – | AI-enhanced software | Health | patient data infrastructure | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||||
Custom AI inference chips | – | – | – | Lamb Labs builds custom chips for AI inference and says it converts autoregressive models into diffusion architectures. The company claims its first FPGA prototype runs on a Kria KV260 board and fits an 8B-parameter model under 10 watts. It presents custom ASICs as the final hardware target and says | B2B | Tyler Bosmeny sources: 1 | AI Research, Dev tools for AI Agents | – | – | Hardware | Hardware | custom AI chips | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
Agent control plane for IT teams | – | – | – | Decawork is an agent control plane for IT teams that deploys, governs, and maintains AI agents across a company. The platform manages identity, credentials, integrations, approval gates, and monitoring through a Decawork gateway. The site says it is backed by Y Combinator and shows fleet management | B2B, Infrastructure | Brad Flora sources: 1 | AI Research, Dev tools for AI Agents, Cloud/DevOps Tools, Security & Compliance Tools | – | – | Developer infrastructure | DevTools | AI agent management | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | ||||
Predictive intelligence for global logistics risk | United States | 1-10 | 2024 | Ekho Labs forecasts global supply chain disruptions 8-12 weeks in advance using community-centered intelligence and multimodal risk modeling. The platform identifies port closures, weather events, and strikes before they impact operations. It provides real-time financial impact analysis and actionab | B2B, Supply Chain and Logistics | Ankit Gupta sources: 1 | Analytics & BI: Data analytics, Supply Chain Visibility & Tracking Tools, Workflow automation | Logistics | – | AI-enhanced software | Manufacturing | supply chain risk forecasting | AI-native application | Software only | – | Self-serve SaaS / software | 1 | 1 founder | ||||
AI-native restaurant back-office OS | – | – | – | Marble is the company formerly known as Truffle, and it positions itself as autonomous back of house software for restaurants. It covers inventory, scheduling, purchasing, finance, and menu operations through an AI-native operating system purpose built for hospitality. The site says it is backed by | B2B | Brad Flora sources: 1 | HR Software, Backoffice automation | – | – | AI-native service | Blue Collar SaaS | back-of-house ops | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Independent git forge with native CLI | – | – | – | GitCafe is a hosted git forge built by one team, including its own git implementation. The public site shows code browsing, diff viewing, pull request inspection, and repository management in a live web application. It also offers a first-party CLI for device-flow sign in, Git credential setup, pull | B2B, Infrastructure | Diana Hu sources: 1 | Dev tools for AI Agents, Collaboration/Productivity, Other | – | – | Developer infrastructure | DevTools | Hosted Git Forge | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | – | – | ||||
AI-driven financial analytics for investment funds | – | – | – | Atlia is a financial analytics platform leveraging AI technology to serve operator-style investment funds in private markets. The platform is specifically tailored for ETA funds and wealth managers, providing them with advanced analytical capabilities. Atlia is backed by Y Combinator, indicating str | Real Estate and Construction, Housing and Real Estate | Jared Friedman sources: 1 2 | – | – | – | – | AI-native service | Blue Collar SaaS | Not applicable | AI-native application | – | – | Services-as-software (AI-native service) | 1 | 1 founder | |||
Infrastructure for automated research via autoresearch agents | United States | 1-10 | 2026 | hiloop provides snapshottable, forkable compute with built-in observability for autoresearch, where agents propose, run, and verify experiments against a chosen metric. The platform lets teams bring their own harness or use hiloop's, provisioning compute, maintaining reproducibility, and tracking ev | B2B, Infrastructure | Ankit Gupta sources: 1 | AI Research, Dev tools for AI Agents | – | Developer infrastructure | DevTools | autoresearch platform | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | |||||
Open-source MCP gateway for AI agents | United States | 1-10 | 2026 | Executor is an open-source MCP gateway that allows any agent speaking MCP, such as Claude Code, Cursor, or Codex, to point at one endpoint and reach every connected tool. It provides a unified integration management layer with authentication, policies, and team sync, eliminating the need to configur | B2B, Infrastructure | Jared Friedman sources: 1 | API Development & Integration Platforms, Collaboration/Productivity, Workflow automation | – | – | Developer infrastructure | DevTools | integration management | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 1 | 1 founder | ||||
AI-native workflow platform for CPA firms | United States | 1-10 | 2025 | Luca IQ is an AI-powered workflow platform for CPA firms that provides a client portal, auto-drafted workpapers, e-signatures, and an IRS Authorized e-filing tax engine. Its AI-native tax engine enables firms to go from client intake to a review-ready 1040 in 30 minutes, with every return reviewed b | B2B, Finance and Accounting | Jared Friedman sources: 1 | Accounting Tech, AI Research, Workflow automation | – | – | AI-native service | Fintech | tax workflow automation | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI agents clearing U.S. government application backlog | United States | 1-10 | 2026 | Stratum builds AI agents that review government applications end-to-end, processing permits, licenses, patents, drug approvals, and benefits claims in seconds instead of weeks or months. The platform runs hundreds of AI agents in parallel against a government backlog, summarizing each file for a hum | Government | Jared Friedman sources: 1 | AI Research, Workflow automation | Government | – | AI-native service | Legal | application review agents | AI agent for a vertical | Software only | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
Institutional marketplace for GPUs and AI hardware | United States | 1-10 | 2026 | Stoa operates a request-for-quote (RFQ) marketplace where institutions buy and sell GPUs (H100, H200, B200, B300, A100, GB200 NVL, L40S, A6000, V100) with verified counterparties and a full audit trail. The platform provides market intelligence on aggregated pricing, volume, condition, and regional | Fintech | Jon Xu sources: 1 | Other | Consumer Electronics, Fintech, Analytics | – | Marketplace | Hardware | GPU RFQ marketplace | AI infrastructure / tooling | Software only | – | Marketplace | 3 | 3 founders | ||||
AI sales coach for in-person field reps | United States | 1-10 | 2025 | COACH provides an AI coach that records every in-person sales meeting and turns it into precise, personalized coaching — highlighting strengths, objections, and what to work on next. Managers can see and coach 100% of what happens in the field, identifying struggling reps and prioritizing coaching o | B2B, Sales | Jon Xu sources: 1 | Sales Enablement Tools | – | – | – | AI-enhanced software | CRM & Sales | AI sales coaching | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||
Engineered diamond wafers for advanced hardware | United States | 1-10 | 2026 | Kara grows high-purity single-crystal diamond wafers for advanced hardware. Used in data centers, aircraft, spacecraft, RF electronics, power devices, and lasers, its diamond moves heat up to 5x better than copper, helping critical systems run cooler and more reliably. The company is turning diamond | Industrials | Brad Flora sources: 1 | Other | B2B, Manufacturing | – | Hardware | Hardware | diamond wafers | Hardware with AI | Hardware / physical product | – | Hardware | 3 | |||||
Turns security cameras into automated 24/7 workforce | United States | 1-10 | 2026 | OpenVector transforms existing security cameras into an automated 24/7 workforce without requiring any new hardware. Users describe a task in plain English, and OpenVector builds a custom AI vision model to monitor the feed and take immediate action when important events are detected. The OpenVector | B2B, Infrastructure | Jon Xu sources: 1 | AI Research, Security & Compliance Tools, Workflow automation | Logistics | – | AI-native service | Hardware | video intelligence appliance | AI-native application | Software only | – | Hardware | 2 | 2 founders | ||||
Vaccines for any cancer or infection | USA | 1-10 | 2026 | TareBio develops personalized or population-level vaccines for any disease in weeks by changing only one input: the immune imprint. Instead of predicting which antigens might work, the platform reads immune cells already fighting the disease in the body and reverse-engineers the antigens that activa | Healthcare, Drug Discovery and Delivery | Ankit Gupta sources: 1 | AI Research, Healthcare Operations & Revenue Cycle Management, Clinical Decision Support Tools | – | – | Biotech | Health | personalized vaccines | Not primarily AI | Software only | – | Self-serve SaaS / software | 1 | 1 founder | ||||
Investment platform for sports and trading cards | United States | 1-10 | 2026 | tash creates professionally constructed portfolios of iconic, investment-grade sports and trading cards, allowing investors to buy and sell shares without physically handling cards. The platform offers diversified indexes (tash25, GOAT Index, Rising Stars Index, Pokémon Index, Vintage Index, TCG Ind | Consumer | Jared Friedman sources: 1 | Investment Banking | – | Fintech | Fintech | trading card portfolios | Not primarily AI | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||||
AI agents creating personalized product demo videos | United States | 1-10 | 2026 | Amorphic Labs builds AI agents that create personalized product demo videos for sales and customer success teams. The agent researches each prospect, navigates the application to record a tailored workflow with personalized seeded data, and outputs a polished narrated demo video ready to send. The c | B2B, Sales | Jared Friedman sources: 1 | Sales Enablement Tools | Sales, B2B | – | AI-enhanced software | CRM & Sales | personalized demo videos | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI web and API pentesting with cloud attack-path analysis | United States | 1-10 | 2025 | Trident is an AI-powered security platform that chains vulnerabilities across AWS, Azure, GCP, web apps, and APIs to map verified attack paths that reach sensitive data. It combines continuous penetration testing with cloud attack-path mapping, providing reproducible exploit proof and automated draf | B2B, Security | Harshita Arora sources: 1 | Security & Compliance Tools | – | – | Developer infrastructure | DevTools | cloud security testing | AI-native application | Software only | – | Developer platform / API / infra | 2 | 2 founders | ||||
AI-powered procurement orchestration with real-time risk prediction | United Kingdom | 1-10 | – | SpaceFlow AI transforms fragmented supplier data into real-time intelligence by integrating email, ERP systems, and open-source feeds. Its agentic-orchestration engine combines graph analytics and large-language models to predict logistics disruptions and optimize procurement workflows. The platform | B2B, Supply Chain and Logistics | Harshita Arora sources: 1 | Procurement & Supplier Management Platforms, Workflow automation, Analytics & BI: Data analytics | Logistics | – | – | AI-enhanced software | Manufacturing | supplier data orchestration | AI-native application | Software only | – | Self-serve SaaS / software | 3 | 3 founders | |||
Smart OS for auto repair shops | United States | 1-10 | 2026 | CarSignal is a shop management platform for independent auto repair shops, replacing the fragmented stack of tools shops currently use. It integrates booking, intake, quoting, parts ordering, invoicing, payments, and customer communication into one AI-powered system. The company monetizes through a | B2B | Brad Flora sources: 1 | Other | Automotive, B2B, Consumer, Payments, Operations | – | AI-enhanced software | Blue Collar SaaS | shop management platform | AI-native application | Software only | – | Self-serve SaaS / software | 1 | 1 founder | ||||
AI training environments for chip design | United States | 1-10 | 2026 | Standard Machines builds reinforcement learning environments and rigorous evaluations where AI models can learn to design chips across architecture, microarchitecture, design, verification, and physical design domains. The company was accepted into Y Combinator's Summer 2026 batch and was founded by | B2B | Ankit Gupta sources: 1 | AI Research | – | – | AI research | DevTools | RL Environments for Chip Design | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 1 | 1 founder | ||||
Verifiable compute platform for confidential, platform-agnostic systems | – | 1-10 | 2025 | Caution offers a verifiable compute platform that enables cryptographic proof of computation results. The platform is designed to replace trust assumptions in modern systems with cryptographic verifiability. Products are scheduled for launch in late 2025. | B2B, Infrastructure | Brad Flora sources: 1 | Security & Compliance Tools, AI Research, Dev tools for AI Agents | – | – | Fintech | Fintech | verifiable compute platform | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | ||||
AI co-chemist that automates computational chemistry workflows | United States | 1-10 | – | Rasyn offers Marigold, an AI platform that acts as a co-chemist for research scientists by automatically selecting and executing computational chemistry tools. Users describe their research need and Marigold handles tool orchestration, returning results in organized panels. The company is a Y Combin | Healthcare, Drug Discovery and Delivery | Ankit Gupta sources: 1 | AI Research, Other | – | – | AI-enhanced software | Health | computational chemistry assistant | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Autonomous interceptor drones for critical infrastructure defense | United States | 1-10 | 2026 | IMPACT DRONES builds autonomous interceptor drones that ship in a sealed box and launch in seconds to kinetically neutralize hostile UAVs. Its containerized defense system includes two interceptors: HUNTER for slow, low-altitude swarm threats and SABLE, a turbine-powered pursuit interceptor for fast | Industrials, Defense | Tyler Bosmeny sources: 1 | Security & Compliance Tools, AI Research, Other | – | – | Hardware | Hardware | autonomous interceptor drones | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
Personalized research lab for complex patients | United States | 1-10 | 2026 | Omanta assembles a dedicated team of PhD-level scientists for each individual patient case, collecting and organizing clinical history, pathology, imaging, and molecular datasets into a patient-specific analytical view. It identifies diagnostic gaps, connects disease biology to the strongest evidenc | Healthcare | Diana Hu sources: 1 | AI Research, Healthcare Operations & Revenue Cycle Management, Clinical Decision Support Tools | Healthcare | – | Biotech | Health | personalized research service | AI-native application | Software only | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
Agent analytics for real user outcomes | United States | 1-10 | 2026 | Buildbox helps product teams improve the human-agent experience by analyzing user intent, agent behavior, and outcomes to find where users get stuck or lose trust, then turning those findings into ranked, reproducible issues that teams can fix. It identifies failed user journeys hidden behind succes | B2B, Analytics | Jon Xu sources: 1 | Analytics & BI: Data analytics, AI Research, Customer Support | Analytics | – | AI-enhanced software | DevTools | agent experience analytics | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Michigan-based home care and disability support | United States | 1-10 | 2026 | Michigan Home Help provides in-home care and support services for older adults and people with disabilities in Michigan. The site presents services such as personal care, companionship, homemaking, and assistance with daily activities. Public website content does not show pricing, ownership details, | Healthcare | – | Other | – | – | – | AI-native service | Health | in-home care services | Not primarily AI | Software only | – | Services-as-software (AI-native service) | – | – | |||
AI that finds and fixes OS-level vulnerabilities across device fleets | United States | 1-10 | 2026 | Palisade watches a fleet at the kernel (syscalls, eBPF traces, process and memory events, network packets), finds operating-system vulnerabilities other tools miss, and applies the fix across every endpoint in minutes. It is backed by Y Combinator (S26). Its founder is Fnu Prince. | B2B, Security | Jon Xu sources: 1 | Security & Compliance Tools, Cloud/DevOps Tools | B2B | – | Developer infrastructure | DevTools | kernel vulnerability management | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 1 | 1 founder | ||||
Desktop app to hear and steer coding agents | United States | 1-10 | 2026 | Agent FM is a desktop app that gives engineers one group chat to hear, steer, and interact with their coding agents running Claude Code, Codex, and OpenCode. It passively observes session output in a separate process and provides live audio updates, voice-to-text transcription anywhere on a Mac or W | B2B, Engineering, Product and Design | Brad Flora sources: 1 | – | Productivity | – | Developer infrastructure | DevTools | coding agent interface | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Advanced metal additive manufacturing for aerospace, defense, energy | United States | 1-10 | 2026 | Ultrasonium builds a metal 3D printing platform using acoustic molding technology for high-performance metal parts. Its contactless acoustic manipulation approach avoids high-powered lasers, enabling production of complex geometries. The company serves aerospace, defense, and energy systems where pe | Industrials, Manufacturing and Robotics | Diana Hu sources: 1 | Manufacturing | Manufacturing, Robotics | – | Hardware | Manufacturing | acoustic metal 3D printing | Hardware with AI | Hardware / physical product | – | Hardware | 4 | |||||
Decentralized market making engine for perp DEXes | United States | 1-10 | 2025 | Arbital lets users deploy automated, maker-only liquidity strategies on perpetual DEXes to generate trading volume and farm points without needing to actively trade. It abstracts market-making complexity historically requiring quant teams and low-latency infrastructure into configurable TWAP-based b | Fintech, Consumer Finance | Harshita Arora sources: 1 | – | – | – | Fintech | Fintech | automated liquidity strategies | AI-native application | Software only | – | Self-serve SaaS / software | 3 | |||||
Earned Intelligence gateway routing LLM requests to lowest-cost model | United States | 1-10 | 2026 | Riften is an OpenAI- and Anthropic-compatible gateway that routes each LLM request to the lowest-cost model capable of completing it, using open-weight models Riften hosts whenever they suffice. Because it sits in the request path, real task results create training evidence the company controls, whi | B2B, Infrastructure | Harshita Arora sources: 1 | AI Research, Dev tools for AI Agents | – | – | – | DevTools | AI agent frameworks | – | – | – | – | 1 | 1 founder | ||||
AI workspace for government contract capture and BD | United States | 1-10 | – | chromie gives government contractors one workspace to find, qualify, and pursue federal and SLED opportunities. It monitors SAM.gov and state/local portals continuously, scoring solicitations against company profiles and analyzing recompetes with intelligence. Backed by Y Combinator (YC S26). | B2B | Harshita Arora sources: 1 | CRM Platforms, Sales Enablement Tools, Marketing & Advertising Tech, Recruiting Software, HR Software, Payments & FinOps Platforms, Analytics & BI: Data analytics, Cloud/DevOps Tools, Collaboration/Productivity, Commerce Platforms, Security & Compliance Tools, Other, Customer Support, Backoffice aut | Government, Fintech | – | Marketplace | CRM & Sales | government contracting platform | AI-native application | Software only | USD 500,000 | Self-serve SaaS / software | 1 | 1 founder | ||||
MCP providing external context beyond web search | United States | 1-10 | 2026 | Click builds a Model Context Protocol (MCP) server that gives AI agents access to data sources web search alone misses — LinkedIn activity, YouTube transcripts, live flight fares, financial datasets, and more. It connects 11+ data sources through a single MCP server compatible with Codex, ChatGPT, a | B2B, Analytics | Harshita Arora sources: 1 | Analytics & BI: Data analytics, AI Research, Cloud/DevOps Tools, Collaboration/Productivity, Workflow automation | – | – | Developer infrastructure | DevTools | contextual data server | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 1 | 1 founder | ||||
AI-native radiology practice | United States | 1-10 | 2025 | Radley is an AI-native radiology practice that uses AI to draft reports before a radiologist opens the case, then delivers signed reports in minutes. The company is acquiring an existing radiology practice to reach $4.3M in annualized revenue and rebuilding it with AI agents from the ground up. Radl | Healthcare | Tyler Bosmeny sources: 1 | AI Research, Healthcare Operations & Revenue Cycle Management, Clinical Decision Support Tools | B2B, Healthcare | – | AI-native service | Health | AI report drafting | AI-native application | Software only | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
Embodiment-agnostic robot brain for physical industries | United States | 1-10 | 2026 | Neuromorphic provides a universal robot brain that lets robots understand plain-language requests and execute tasks across different robot bodies including quadrupeds, wheeled robots, and humanoids. An onboard LLM converts instructions into safe robotic workflows with reusable skills for navigation, | Industrials, Manufacturing and Robotics | Diana Hu sources: 1 | Robotics, AI Research | – | – | Hardware | Hardware | universal robot brain | AI agent for a vertical | Hardware / physical product | – | Hardware | 3 | 3 founders | ||||
AI that automates commercial insurance underwriting workflow | United States | 1-10 | 2025 | Qlo uses AI to run the commercial underwriting workflow from submission to renewal for submission-heavy MGAs and program administrators. The platform converts Excel raters into live pricing engines, automates submission intake by extracting data from broker attachments in under 2 minutes, and evalua | Fintech, Insurance | Gustaf Alstromer sources: 1 | AI Research, Insurance tech | – | – | Fintech | Fintech | underwriting automation | AI-native application | Software only | – | Self-serve SaaS / software | 2 | |||||
Zero US-part sovereign satellite constellation for D2C | Singapore | 1-10 | 2026 | Exosat manufactures low-cost communication satellites with zero U.S.-origin content, enabling export to and launch from any nation. Its satellites integrate with existing 3GPP infrastructure and spectrum to provide direct-to-cell, IoT, and broadband backhaul to standard devices without custom gatewa | Industrials, Aviation and Space | Brad Flora sources: 1 | – | – | – | Hardware | Hardware | low-cost satellites | Hardware with AI | Hardware / physical product | – | Hardware | 1 | 1 founder | ||||
Automatic robot cell fault diagnosis and recovery | United States | 1-10 | 2025 | Dawn Industries builds VIM, a system that reads fault codes from robot cells, identifies the root cause by cross-referencing machine manuals, live device signals (PLC, HMI, robot, sensors, drives), and cell history, then recommends one safe recovery action for the operator. VIM runs on existing cont | Industrials, Manufacturing and Robotics | Diana Hu sources: 1 | Manufacturing, AI Research, Robotics | Manufacturing, Robotics | – | Hardware | Manufacturing | fault diagnosis system | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
APIs for Physical AI data quality analysis | United States | 1-10 | 2026 | Hebbian Robotics builds APIs that turn Physical AI footage into queryable measurements, enabling data providers to evaluate data quality without training a robotics model. Its Pareto platform lets teams browse, search, and run automated consistency algorithms on robotics datasets. The company is bac | Industrials, Manufacturing and Robotics | Diana Hu sources: 1 | AI Research, Dev tools for AI Agents | Robotics | Developer infrastructure | Hardware | Data Quality API | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | |||||
AI research lab training foundation models for quantitative trading | United States | 1-10 | 2026 | Prodigy Research trains the world's best foundation model for quantitative finance. Its proprietary trading model and agent outperform Claude Fable and GPT-5.6 Sol on trading and financial-reasoning benchmarks. In live trading, the AI quant trader beats a 90th-percentile Jane Street trader and more | Fintech | Brad Flora sources: 1 | AI Research | Finance | – | Fintech | Fintech | autonomous trading agent | AI agent for a vertical | Software only | – | Developer platform / API / infra | 2 | 2 founders | ||||
AI-native debt collection with gentle automation | Norway | 1-10 | 2026 | Audun automates the full debt collection cycle -- outreach, negotiation, payment plans, and payouts -- using AI to send well-timed reminders on the channels each debtor uses and propose fitting payment plans. It flags financial hardship cases and escalates them to human operators with full conversat | Fintech | Vivian Midha Shen sources: 1 | Payments & FinOps Platforms, Other | Fintech | – | Fintech | Fintech | debt collection automation | AI-native application | Software only | – | Services-as-software (AI-native service) | 4 | |||||
Open-source Rust terminal AI coding agent | United States | 1-10 | 2026 | jcode is an open-source AI coding agent for the terminal written in Rust, enabling users to run dozens of agents in parallel with durable memory, background tasks, and agent swarms. It is built by solo founder Jeremy Huang under Solo Labs, a Y Combinator S2026 company, and has grown to 16.3k GitHub | Consumer | Brad Flora sources: 1 | AI Research, Dev tools for AI Agents | – | – | Developer infrastructure | DevTools | terminal coding agents | AI agent for a vertical | Software only | – | Developer platform / API / infra | 1 | 1 founder | ||||
Launches and operates AI-native law firms | United States | 1-10 | 2026 | Erinys provides the software, staff, back office, working capital and growth infrastructure required to launch and operate a turnkey law firm. It enables lawyers to start their own firm with Biglaw-level pay and equity partner ownership from day one without sacrificing steady income. The company is | B2B, Legal | Diana Hu sources: 1 | Legal Tech, AI Research, Workflow automation | Legal | – | AI-native service | Legal | law firm launch platform | AI-native application | Software only | – | Self-serve SaaS / software | – | – | ||||
Mass-produced solar-powered waterless autonomous GPU data centers for desert and orbit | United Kingdom | 1-10 | 2026 | Pacific builds mass-produced, solar-powered, waterless, autonomous GPU pods designed to operate in the desert today and in orbit next, using the vertical supply chain that got SpaceX to orbit. It also develops NOVA, an AI-powered systems engineering platform that combines frontier language models wi | Industrials | Brad Flora sources: 1 | AI Research, Cloud/DevOps Tools, Analytics & BI: Data analytics | – | – | – | Hardware | Hardware | autonomous GPU pods | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | |||
AI-native freight brokerage specializing in hard-to-move hazmat loads | United States | 1-10 | 2026 | Peer Freight (brand "Peer") is an AI-native freight brokerage that quotes freight, finds the right trucking companies, tracks shipments, and handles problems from pickup through delivery for shippers. The brokerage specializes in hazmat and oversize loads while also covering reefer, dry van, flatbed | B2B, Supply Chain and Logistics | Harshita Arora sources: 1 | Freight management | – | – | AI-native service | Manufacturing | AI freight brokerage | AI-native application | Software only | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
Real-time shared workspace for teams and AI agents | United States | 1-10 | 2026 | Mosaic provides a shared, persistent environment where teams and their AI agents work together in real time, letting users create and connect unique agents, co-pilot code alongside colleagues, and bridge custom agents with external partner agents. Its main product, Ocean, gives people and their codi | B2B | Tyler Bosmeny sources: 1 | Collaboration/Productivity | – | – | – | Developer infrastructure | DevTools | collaborative coding platform | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | |||
Generates robotics training data via full improvement loop | United States | 1-10 | 2026 | Enact generates the data that makes robotics models reliable in the real world. The company runs the full improvement loop: roll out policies on tasks, identify the states where they fail, and generate targeted demonstration and recovery datasets, then train, evaluate, and repeat. It evaluates model | Industrials, Manufacturing and Robotics | Jon Xu sources: 1 | AI Research, Robotics, Dev tools for AI Agents | Robotics | – | AI research | Hardware | demonstration datasets | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | ||||
AI firewall for companies moving money onchain | Israel | 1-10 | 2026 | Verdict Machine uses AI to understand each financial institution's complete on-chain environment, assess its cyber risk and generate tailored controls. AI agents continuously map the wallets, tokens, contracts, and vendors an institution's funds touch, then author policies that provide a verdict on | B2B, Security | Brad Flora sources: 1 | Security & Compliance Tools, AI Research, Payments & FinOps Platforms | – | – | Fintech | Fintech | on-chain security solutions | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Stock market API with extensive financial data | – | – | – | Financial Datasets provides a stock market API that offers real-time and historical financial data for over 30,000 tickers spanning more than 30 years. The API includes financial statements, equity prices, insider transactions, SEC filings, and additional financial data. The company serves a wide ra | B2B | Brad Flora sources: 1 | Analytics & BI: Data analytics, Other | – | Fintech | Fintech | financial data API | AI-native application | Software only | – | Developer platform / API / infra | 1 | 1 founder | |||||
Robots that learn new factory tasks from a single human demonstration | United States | 1-10 | 2026 | Shiraz AI deploys robots that learn new tasks from a single human demonstration in the factory, starting in contract manufacturing where lines change every week and both traditional automation and today's VLAs fall over. The company is building the next generation of robotic foundation models that e | Industrials, Manufacturing and Robotics | Jon Xu sources: 1 | Robotics, Manufacturing, AI Research | Robotics, Manufacturing | – | Hardware | Manufacturing | robotic task learning | Foundation model / frontier research | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
Local influence network connecting businesses with nearby creators | United States | 1-10 | 2025 | TryNearby connects local businesses with creators who live nearby. Restaurants subscribe monthly and automatically get booked visits from local creators who post and review, compounding into a discovery engine on TikTok, Instagram, Google, and Yelp. It handles matching, scheduling, and management of | B2B, Marketing | Brad Flora sources: 1 | Marketing & Advertising Tech | – | – | Marketplace | Blue Collar SaaS | creator marketing platform | Not primarily AI | Software only | – | Marketplace | 3 | 3 founders | ||||
World models that train and evaluate robots in virtual physics | United States | 1-10 | 2026 | Moving Atoms builds world models (Atom 1 and Atom 2) that let robots learn, understand, and act from uploaded video. Its data augmentation service re-films one training take across environments with motion, camera, and physics locked, and its World Action Model rolls the world forward in a physics-a | Industrials, Manufacturing and Robotics | Brad Flora sources: 1 | AI Research, Robotics, Dev tools for AI Agents | Robotics | – | Hardware | Hardware | world models | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
Manages AI workers with roles, managers, and measurable outcomes | United States | 1-10 | 2026 | Tenor is a Y Combinator-backed platform that lets organizations give AI systems defined roles, managers, guardrails, budgets, and measurable outcomes. It connects employee AI use, completed work, human interventions, and AI spend to business outcomes so leaders can measure ROI rather than just adopt | B2B | Jon Xu sources: 1 | AI Research, Dev tools for AI Agents, Workflow automation | – | – | AI-native service | DevTools | AI workforce management | AI-native application | Software only | – | Self-serve SaaS / software | 3 | |||||
Market-derived RL environments training agents for quant research | United States | 1-10 | 2026 | EdotEnv builds reinforcement learning environments derived from real financial market data to teach AI agents applied ML and long-horizon planning under adversarial noise. It programmatically generates quant research tasks inside these environments, where agents use professional tools and build thei | B2B | Jared Friedman sources: 1 | AI Research, Analytics & BI: Data analytics | – | – | – | Fintech | Fintech | financial RL environments | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 1 | 1 founder | |||
Monetizes AI agent interaction data for AI labs | United States | 1-10 | 2026 | Magma enables any company building AI agents to monetize its data in a few clicks. It packages and licenses agent interaction data — the traces, corrections, and workflows agents produce — to AI labs and researchers, who pay for records of how real work happens inside real products. Companies earn a | B2B, Infrastructure | Harshita Arora sources: 1 | AI Research, Other | – | – | Marketplace | DevTools | data monetization platform | AI infrastructure / tooling | Software only | – | Marketplace | 1 | 1 founder | ||||
AI-native insurance for the compute economy | United Kingdom | 1-10 | 2026 | Princeps builds the price of compute risk — a live benchmark for downtime, failure, and model-output liability, built from telemetry instead of loss history. It builds the underwriting layer for AI infrastructure, modeling and pricing exposure, structuring products, and placing them with carriers. I | Fintech, Insurance | Vivian Midha Shen sources: 1 | Insurance tech, AI Research, Analytics & BI: Data analytics | – | – | Fintech | Fintech | compute risk benchmarking | AI infrastructure / tooling | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI agents for compliance at institutional brokerages | United States | 1-10 | 2026 | Toven builds AI agents that handle manual, data-intensive compliance work for institutional trading firms, reading from the chat, voice, surveillance, and archiving systems a desk already runs on with no migration. Agents assemble context and evaluate each alert, report, and question, escalating onl | Fintech, Banking and Exchange | Brad Flora sources: 1 | Compliance Tech, AI Research, Workflow automation | Fintech | – | Fintech | Legal | compliance automation | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI-native proxy voting and governance intelligence for institutional investors | United States | 1-10 | 2026 | Pennant gives institutional investors, public companies, and corporate advisors voting and governance intelligence to act on their own principles at scale. It is an AI-native proxy voting platform offering AI-powered proposal and AGM analysis, custom policy execution, and portfolio management tools, | Fintech, Asset Management | Brad Flora sources: 1 | AI Research, Analytics & BI: Data analytics | Fintech, Analytics, Consumer Finance | – | AI-native service | Legal | proxy voting platform | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Real-time voice translation and lip-sync dubbing lab | – | 1-10 | 2026 | Familiar builds world models for accurate humans, offering a dubbing model that translates videos and livestreams into 25 languages while preserving the original voice and lip movements in real time. Its research spans joint audio-visual generation (JAM-Flow), real-time human animation (SoulX-LiveAc | B2B | Harshita Arora sources: 1 | AI Research, Marketing & Advertising Tech, Other | – | AI-enhanced software | Other | real-time dubbing | AI-native application | Software only | – | Self-serve SaaS / software | 3 | 3 founders | |||||
AI-native engineering firm accelerating data center development | United States | 1-10 | 2026 | Marengo is an AI-native engineering firm that reduces traditional pre-construction design cycles for data centers from 10-12 months to 5-6 months by automating iterative engineering processes. It delivers site due diligence, feasibility, concept design, and FEED/permitting design to help clients vis | Industrials, Energy | Diana Hu sources: 1 | AI Research, Workflow automation | Design | – | AI-native service | Manufacturing | data center design | AI-native application | Software only | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
Expert-driven evaluation as a service for enterprise AI | United States | 1-10 | – | DeepReach.ai provides expert-driven evaluation as a service for enterprise AI. It features real-world, dynamic benchmarks with live data updates and continuous ROI tracking. The platform integrates expert feedback and cultural context to ensure reliable, scalable AI performance. | B2B | – | AI Research, Other | – | Hardware | Hardware | AI Research Hardware | Hardware with AI | Hardware / physical product | – | Hardware | – | – | |||||
Mobile-first 1-minute anime shorts produced daily with AI | United States | 1-10 | 2025 | Mochi is a mobile-first entertainment platform for vertical anime shorts, producing new shows daily with AI that have hit 300M+ views organically. Users scroll to discover shows and binge bite-sized one-minute episodes, unlocking them with either coins or a subscription. The app is free on iOS and A | Consumer, Content | Brad Flora sources: 1 | Other | Consumer | – | Consumer | Consumer | vertical anime shorts | AI-native application | Software only | – | Consumer app | 2 | 2 founders | ||||
Engineering intelligence platform for the AI-coding era | United States | 1-10 | 2026 | Mentlio is an engineering intelligence platform that gives engineering leaders a real-time picture of how teams use AI-coding tools like Cursor, Claude Code, Codex, and Gemini, turning scattered usage into measurable adoption and productivity impact. It aims to cut wasted AI spend through intelligen | B2B | Pete Koomen sources: 1 | AI Research, Dev tools for AI Agents, Analytics & BI: Data analytics, HR Software | – | – | Developer infrastructure | DevTools | AI usage analytics | AI infrastructure / tooling | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Photonic hardware for AI and quantum infrastructure | United States | – | 2026 | Dipole Labs builds optical switching and compute modules that make AI clusters faster and more energy-efficient, and photonic hardware for next-generation AI and quantum computing systems. It aims to preserve light as the medium for data transfer, arguing that current silicon infrastructure is the b | Industrials | Jared Friedman sources: 1 | AI Research, Cloud/DevOps Tools, Analytics & BI: Data analytics, Dev tools for AI Agents | – | – | – | Hardware | Hardware | optical switching modules | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | |||
Drones that clear clouds over solar farms | United States | 1-10 | 2026 | Meteoric operates drones that fly into low and mid-altitude clouds over solar farms, altering cloud droplets to reduce cloud reflectivity and allow more sunlight to reach solar panels, producing a measurable output increase without chemicals or new infrastructure. Founded in 2026 by Mete Karslioglu | Industrials, Climate | Gustaf Alstromer sources: 1 | Clean Power Software Platforms, AI-Driven Threat Detection & Response, Sustainable Fuels & Alternative Energy, Cloud/DevOps Tools, Other | Drones | – | Hardware | Hardware | drone cloud clearing | Hardware with AI | Hardware / physical product | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
Managed procurement and inventory for hardware teams | India | 1-10 | 2026 | Waybill is a YC Summer 2026 company that runs the full procurement-to-dock loop for hardware teams: a customer sends a part, a spec, or a BOM, and Waybill sources it, pulls quotes, routes approvals, pays the supplier, handles freight and customs, tracks it to the dock, and keeps the stock count upda | B2B, Supply Chain and Logistics | Jared Friedman sources: 1 | Procurement & Supplier Management Platforms | Logistics | – | Marketplace | Hardware | procurement logistics | AI-native application | Software only | – | Marketplace | 2 | 2 founders | ||||
Builds GitNexus, the nervous system for agent context | United States | 1-10 | 2026 | Akon Labs (YC S26) builds GitNexus, an open-source code intelligence engine that indexes any codebase into a knowledge graph of every dependency, call chain, cluster, and execution flow so AI agents never miss code. GitNexus runs local-first in the browser or self-hosted, making zero external calls | B2B | Jon Xu sources: 1 | Dev tools for AI Agents, Analytics & BI: Data analytics, Collaboration/Productivity, Other | – | Developer infrastructure | DevTools | code intelligence engine | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | |||||
AI claims adjuster for regulated insurance backed by YC | United States | 1-10 | 2026 | Veltha builds decisioning infrastructure for insurance carriers and TPAs, producing structured, citation-backed findings on compensability, causation, and apportionment so adjusters have a defensible basis for every decision. Its Compliance AI checks every claim against the actual regulation (FCIC, | Fintech, Insurance | Gustaf Alstromer sources: 1 | Compliance Tech, Insurance tech | – | – | Fintech | Fintech | claims automation | AI-native application | Software only | – | Developer platform / API / infra | 2 | 2 founders | ||||
AI-powered HTS classification with 55% tariff reduction | – | 11-50 | 2024 | Tarifflo uses AI to classify products under the Harmonized Tariff Schedule, leveraging 1 billion+ rows of trade data and 300,000+ court rulings. The platform delivers accurate HTS, Schedule B, and ECCN codes with instant access to compliance documents. It reduces tariffs by 55% on average and provid | B2B, Supply Chain and Logistics | Vivian Midha Shen sources: 1 | Compliance Tech, AI Research, Workflow automation | – | – | AI-native service | Legal | HTS classification tool | AI-native application | Software only | – | Services-as-software (AI-native service) | 1 | 1 founder | ||||
Private foundation models trained on customer event data | United States | 1-10 | 2026 | Lyon trains a foundation model from scratch on a company's customer event data, and the model runs in the customer's own cloud so the customer owns the intelligence. Every downstream task — churn, credit risk, fraud, collections, income, cross-sell — comes from the same model rather than months-long | B2B, Analytics | Gustaf Alstromer sources: 1 | AI Research, Analytics & BI: Data analytics | Fintech | – | Fintech | Fintech | custom foundation models | Foundation model / frontier research | Software only | – | Developer platform / API / infra | 1 | 1 founder | ||||
AI-powered operating system for the skilled trades helping appliance technicians. | United States | 1-10 | 2026 | Bernard is an AI-powered operating system for the trades that helps technicians diagnose appliances faster, automate documentation, and source parts instantly to eliminate callbacks and paperwork. At its center is Pre-ID, which combines the exact appliance and its symptoms with repair history, simil | B2B, Operations | Jared Friedman sources: 1 | AI Research, Workflow automation, Customer Support, Other | – | – | – | AI-native service | Blue Collar SaaS | appliance repair OS | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||
Personal AI sales agent for every marketplace visitor | United States | 1-10 | 2026 | Palisade spins up a dedicated personal sales agent for every visitor to an online marketplace. The agents take real actions on the platform — clicking items, pulling up listings, adding to cart, making bookings — learning each customer's taste, remembering them across visits, and reaching out by ema | B2B, Engineering, Product and Design | Brad Flora sources: 1 | Sales Enablement Tools, CRM Platforms, Marketing & Advertising Tech | Sales | – | Marketplace | CRM & Sales | personal sales agent | AI agent for a vertical | Software only | – | Services-as-software (AI-native service) | 1 | 1 founder | ||||
Extrapolative AI biotech replacing injections with pills | United States | 1-10 | – | WonderTx is an AI-native biotech building extrapolative frontier models that reason beyond their training data to unlock first-in-class drugs, replacing needles with pills for drugs like insulin and Ozempic. It targets a $200B market of treatable diseases and validated human biology that currently l | Healthcare, Therapeutics | Pete Koomen sources: 1 | AI Research, Healthcare Operations & Revenue Cycle Management | Drug Discovery | – | Biotech | Health | oral drug discovery | Foundation model / frontier research | Software only | – | Services-as-software (AI-native service) | 1 | 1 founder | ||||
Pocket-sized battery-powered AI cameras that catch asset damage | United States | 1-10 | 2026 | DREAM™ automatically photographs every asset passing through a gate, identifies it, and reconstructs it into a 3D condition record, using AI to flag new dents, scrapes, and changes that human teams might miss. It preserves every condition record and gives each location one clear source of truth. The | B2B | Jared Friedman sources: 1 | AI Research, Other | – | – | AI-native service | Hardware | 3D asset condition records | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Voice AI agents purpose-built for workers' compensation | United States | 1-10 | 2026 | Evergrove provides an AI contact center for workers' compensation, with voice AI agents that run end-to-end calls and accelerate in-case communications across intake, clinical, status, billing, and intel workflows. The agents handle FROI (first report of injury), referrals, DME ordering, T&T orderin | Healthcare | Harj Taggar sources: 1 | AI Research, Customer Support, Workflow automation | – | – | AI-native service | Health | voice AI agents | AI agent for a vertical | Software only | – | Services-as-software (AI-native service) | 2 | 2 founders | ||||
Personal on-iPhone AI assistant that talks to your apps | United States | 1-10 | 2026 | Touchy is a personal AI assistant that lives on the iPhone, sees what the user sees, and talks to the user's other apps to take care of work. Instead of opening ten different apps, users take ten seconds to ask a quick question to Touchy and put the phone away. It is generally available to download | Consumer | Vivian Midha Shen sources: 1 | AI Research, Collaboration/Productivity, Other | – | – | Consumer | Consumer | context-aware assistant | AI-native application | Software only | – | Consumer app | 3 | 3 founders | ||||
AI-powered medical billing for specialty clinics | – | 1-10 | 2026 | Kandor provides AI-powered operational software and billing services that handle the full billing cycle for specialty clinics: eligibility verification, coding review, claims management, denial appeals, and payment posting. The company uses offshore billers at domestic prices and offers upfront cash | Healthcare | – | Payments & FinOps Platforms, HR Software, Other | Healthcare | – | Fintech | Health | billing automation | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Domestic recycled rare-earth permanent magnets for DFARS defense compliance | United States | 1-10 | 2026 | Mass Magnetics manufactures high-performance permanent magnets from domestic and recycled rare-earth feedstocks, reducing dependence on foreign-sourced rare earths. Its process achieves fully densified magnets from recycled powder in as little as 60 seconds while consuming drastically less energy, p | Industrials, Defense | Vivian Midha Shen sources: 1 | Manufacturing | Manufacturing | – | Hardware | Manufacturing | high-performance magnets | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
Drop-in autonomy modules turning FPV drones into autonomous interceptors | United States | 1-10 | 2026 | Vernius builds drop-in hardware modules that convert any existing FPV into an autonomous interceptor, designed for low-cost, high-volume deployment. Its module sits between the receiver and flight controller and provides beyond-visual-range sensing with Autonomous and Operator modes, using a three-p | Industrials, Defense | Brad Flora sources: 1 | AI Research, Robotics | Drones | – | Hardware | Hardware | autonomous interceptor modules | Hardware with AI | Hardware / physical product | – | Hardware | 1 | 1 founder | ||||
Primary care clinic where AI earns clinical autonomy | United States | 1-10 | 2026 | Standard Medical is building a primary care clinic where AI earns clinical authority the way physicians always have, under supervision, one privilege at a time, on evidence. It operates inside the nation's first regulatory framework for clinical AI, based in Utah, and plans to start seeing its first | Healthcare | Tyler Bosmeny sources: 1 | Telemedicine & Virtual Care Platforms, AI Research, Healthcare Operations & Revenue Cycle Management | Healthcare | – | – | AI-native service | Health | AI Primary Care | AI agent for a vertical | Software only | – | Services-as-software (AI-native service) | 1 | 1 founder | |||
Point-of-use contamination destruction for semiconductor manufacturing | United States | 1-10 | 2026 | Aerogen Systems builds modular, point-of-use contamination destruction systems that chemically destroy trace organics and acid gases at the source, eliminating the need for cleanrooms in semiconductor manufacturing. Its Talos reactor destroys airborne contamination wherever wafers sit exposed, with | Industrials | Jon Xu sources: 1 | Other | Manufacturing | – | Hardware | Manufacturing | contamination control systems | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
AI-powered 24/7 phone system for Spanish-speaking businesses | Colombia | 1-10 | 2023 | Callbook AI delivers automated, human-like phone interactions in Spanish for businesses in fintech, logistics, e-commerce, and healthcare. The system integrates with Zoho CRM, Clientify, GoHighLevel, and Shopify to capture call data and automate workflows. It operates 24/7, reduces call center costs | B2B | Jon Xu sources: 1 | AI Research, Customer Support, Sales Enablement Tools, Workflow automation | Fintech, Analytics | – | AI-native service | CRM & Sales | automated call interactions | AI-native application | Software only | – | Services-as-software (AI-native service) | 1 | 1 founder | ||||
AI second brain that runs creator content distribution and engagement | United States | 1-10 | 2024 | Grocalo is an AI tool that manages content distribution, engagement, and growth for creators across Instagram, TikTok, YouTube, Facebook, LinkedIn, Threads, and Snapchat. It cross-posts to every platform a creator publishes on, replies to common comments and DMs, and reposts a creator's best work on | Consumer, Content | Jon Xu sources: 1 | AI Research, Marketing & Advertising Tech, Collaboration/Productivity | – | – | AI-enhanced software | Consumer | content distribution tool | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI-native consultancy embedding custom AI agents into operations | United States | 1-10 | 2026 | Marker embeds with companies, learns how their organization actually works, finds the highest-impact problems, and ships custom AI agents into production in weeks. It automates workflows end-to-end on the systems clients already run, citing a reduction of manual work in product operations by 80% and | B2B, Productivity | Brad Flora sources: 1 | AI Research, Workflow automation, Dev tools for AI Agents | – | – | AI-native service | DevTools | custom AI agents | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 3 | 3 founders | ||||
First social poker app with a built-in feed | United States | 1-10 | 2026 | Snap Poker is the first social poker app, a real-money platform with a feed built in. Players post hands as interactive reels with voiceover and build a following. The company takes zero rake, monetizing like a game rather than a casino. | Consumer, Social | Vivian Midha Shen sources: 1 | – | – | – | – | Consumer | Consumer | social poker platform | AI-native application | Software only | USD 125,000 | Consumer app | – | – | |||
Autonomous hardware test and firmware development agent | United States | 1-10 | 2026 | Hilstart automates electronics bring-up, validation, and firmware development. It builds a specification from your design files that you approve, writes executable hardware tests, and runs them on real hardware via its Tracer test equipment, operating autonomously. Backed by Y Combinator (Summer 202 | Industrials, Manufacturing and Robotics | Jared Friedman sources: 1 | Other | Automotive | – | Hardware | Hardware | hardware test automation | Hardware with AI | Hardware / physical product | USD 1,100,000 | Hardware | 4 | |||||
Consumer decision simulation platform backed by Y Combinator | United States | 1-10 | 2026 | Studio is a consumer decision simulation platform that lets businesses test pricing changes, product launches, and menu updates on a calibrated model of their customers, simulating forward-looking KPIs before committing budget. It models 200 million consumers with 95% forecast accuracy. The company | B2B, Analytics | Jon Xu sources: 1 | Analytics & BI: Data analytics, Other | – | – | Consumer | Consumer | consumer behavior simulation | AI-native application | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
AI-native clinical group for behavioral health practices | United States | 1-10 | 2025 | Allia provides a connected platform for independent behavioral health practices, integrating intake, care documentation, billing, and practice management. It operates a Clinically Integrated Network that brings hundreds of independent practices across all 50 states into one national group, and offer | Healthcare, Healthcare Services | Jon Xu sources: 1 | HR Software, Clinical Decision Support Tools, Health Data Integration & Interoperability Platforms | – | – | Consumer | Health | behavioral health EHR | Not primarily AI | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Live blind arena for real-world computer-use agent evals | United States | 1-10 | 2026 | Coarena is a live arena where anyone can race two top AI computer-use agents, including Fable, Sol, and models not yet released to the public, on the same real browser task and judge which did it better, blind. It runs without a fixed task list to prevent overfitting, and publishes an Elo-ranked lea | B2B, Engineering, Product and Design | Brad Flora sources: 1 | AI Research, Dev tools for AI Agents | Analytics, Consumer, Fintech, Human Resources, Operations, Productivity, Security, Talent | – | – | AI research | DevTools | AI agent racing | AI infrastructure / tooling | Software only | – | Self-serve SaaS / software | 2 | 2 founders | |||
Military exoskeletons that increase soldier strength and endurance | United States | 11-50 | – | Edgerun Industries builds military exoskeletons. Its hip-mounted system assists with every step a soldier takes under combat load, so soldiers can travel farther, carry more, and arrive with more energy to fight. The company is backed by Y Combinator (Summer 2026 batch) with active development acros | Industrials, Defense | Tyler Bosmeny sources: 1 | Robotics, AI Research | Robotics | – | Hardware | Hardware | military exoskeletons | Hardware with AI | Hardware / physical product | – | Hardware | 1 | 1 founder | ||||
independent research and trading firm that trains AI traders | United States | 1-10 | 2026 | Spectre Intelligence is an independent research and trading firm focused on reasoning under uncertainty. It is a multi-strategy trading firm that creates AI traders instead of hiring human ones, currently trading semiconductors and biotech. It operates an evolutionary trading firm model where AI age | Fintech, Asset Management | Ankit Gupta sources: 1 | AI Research, Payments & FinOps Platforms | – | – | Fintech | Fintech | AI trading agents | AI agent for a vertical | Software only | – | Self-serve SaaS / software | 2 | 2 founders | ||||
Model-agnostic AI teammate for Slack and Microsoft Teams | United States | 1-10 | 2026 | OpenTag is an AI coworker that lives in Slack and Microsoft Teams, routing tasks to the best available model from more than eighty options via its Conifer least-cost routing layer, claiming up to 70% cost savings. It keeps full company context so it can answer questions, join calls, and take real wo | B2B | Jared Friedman sources: 1 | AI Research, Collaboration/Productivity, Workflow automation | – | – | AI-enhanced software | DevTools | AI productivity assistant | AI-native application | Software only | – | Self-serve SaaS / software | 3 | 3 founders | ||||
Building spaceports on the Moon and Mars | United States | 1-10 | 2022 | Ethos Space specializes in developing infrastructure for spaceports on the Moon and Mars. Their unique approach involves utilizing local resources to create hard rock landing pads and in-situ propellant. This capability enables safe and affordable logistics for future space industries. | Industrials, Aviation and Space | – | Other | – | – | Hardware | Hardware | lunar infrastructure | Hardware with AI | Hardware / physical product | – | Hardware | 2 | 2 founders | ||||
KV cache transfer inference engine cutting costs 20% | United States | 1-10 | 2026 | OneTriangle provides an inference engine that uses frontier research on KV cache transfer between models to reduce inference costs by 20% and time-to-first-token by 40% versus current standards. It prefills on a small model and decodes on a large one, delivering large-model-quality answers faster an | B2B, Infrastructure | Ankit Gupta sources: 1 | AI Research, Dev tools for AI Agents | – | – | Developer infrastructure | DevTools | inference engine | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 2 | 2 founders | ||||
Robotics research lab building autonomous evaluation rig for robot learning | United States | 1-10 | 2026 | Most Robotic is a robotics research lab pushing what is possible with physical AI. Its product, Instance, is the verification layer for robot learning: given a task and camera footage, it returns a success verdict with evidence for every episode on any robot, so users can trust their data and train | Industrials, Manufacturing and Robotics | Ankit Gupta sources: 1 | AI Research, Robotics, Other | Robotics | – | – | Hardware | Hardware | robot performance verification | AI infrastructure / tooling | Hardware / physical product | – | Self-serve SaaS / software | 2 | 2 founders | |||
RL environments for scientific reasoning and performance engineering | United States | 1-10 | 2026 | Cuebench builds reinforcement learning environments for scientific reasoning and performance engineering, targeting tasks where frontier models still fail more than 80% of the time, such as scientific reasoning, experiment design, and inference engineering. The company is backed by Y Combinator (S26 | B2B | Vivian Midha Shen sources: 1 | AI Research, Dev tools for AI Agents | Analytics, Education, Engineering, Fintech, Healthcare IT, Human Resources, Manufacturing, Productivity | – | AI research | DevTools | scientific RL environments | AI infrastructure / tooling | Software only | – | Developer platform / API / infra | 3 | 3 founders | ||||
Biocomputing company growing large-scale biological neural tissue | United Kingdom | 1-10 | 2025 | Frontier Computing is a biocomputing company growing large-scale neuronal tissue as living hardware with memory baked in at the cellular level. It provides the substrate, interfacing, and cloud infrastructure for third parties to train on its biological neural systems, which are already being traine | Industrials | Harshita Arora sources: 1 | AI Research, Other | – | – | Biotech | Health | biological neural systems | Hardware with AI | Hardware / physical product | USD 10,000,000 | Hardware | 1 | 1 founder |
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