AI-designed peptides for tissue-specific cancer therapy
Design tissue-specific peptides for delivery to triple-negative breast cancer cells; Deliver cytotoxic agents to tumor cells via SORT1 receptor-mediated endocytosis; Test therapeutic payloads including radioisotopes and oligonucleotides in preclinical models; Develop blood-brain barrier shuttle systems for neurodegenerative diseases
First patient dosed in Phase I clinical trial of PQ203 in advanced metastatic cancer; Validated by AstraZeneca and UHN Princess Margaret Cancer Centre; Partnerships with pharma and academic research institutions; Proprietary ProteinStudio™ platform with petascale computing capabilities