Greenstone Biosciences combines human induced pluripotent stem cells (iPSCs) with AI to accelerate drug discovery. Their platform uses 3D organoids and human-relevant cellular models to reduce reliance on animal testing. The company leverages proprietary machine-learning algorithms to guide candidate selection and optimize lead molecules.
Model cardiac diseases using patient-derived cardiomyocytes; Screen for cardiotoxicity using ADMET-AI; Test drug efficacy in pancreatic islet organoids; Evaluate gut permeability in organoid models; Perform hepatotoxicity screening; Conduct CRISPRi/a screens in human iPSC-cardiomyocytes
Co-founded by Dr. Joseph C. Wu (Stanford); Published in Nature and Circulation; Proprietary ADMET-AI algorithm for cardiotoxicity prediction; Offers patient-specific disease modeling; Provides human-relevant, animal-free drug testing platforms