Encycle Therapeutics is a Toronto-based biotech company that focuses on synthesizing drug-like macrocycles and nacellins. Their technology targets intracellular protein-protein interactions, offering potential oral alternatives to existing biologics. The company is developing nacellins for conditions like inflammatory bowel disease and fibrosis.
Develop orally bioavailable inhibitors for IBD; Target SMURF2 for fibrosis treatment; Collaborate with pharmaceutical companies for nacellin screening; Create alternatives to monoclonal antibodies; Explore drug-like properties of nacellins
Acquired by Zealand Pharma; Collaborated with multiple pharmaceutical companies; Raised funding from Takeda Ventures