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Bicycle Therapeutics Analysis

What is Bicycle Therapeutics?

Precision-guided peptide therapeutics for solid tumors and beyond
Location
Cambridge, United Kingdom
Employees
201-500
Founded
2009

Product Features & Capabilities

  • Bicycle® Toxin Conjugates (BTC®) targeting Nectin-4
  • Bicycle® Tumor-Targeted Immune Cell Agonists (Bicycle TICA®) targeting Nectin-4 and CD137
  • Bicycle® Radio Conjugates (BRC™) for radiopharmaceuticals
  • Peptide therapeutics using phage display technology

Use Cases

Target Nectin-4 expressing tumors with BTC conjugates; Treat EphA2-positive cancers with BTC conjugates; Activate CD137 in tumor microenvironment via Bicycle TICA®; Deliver radiopharmaceuticals using BRC™ technology; Develop therapies for anti-infective, cardiovascular, and CNS diseases through partnerships

Other Considerations

Clinical-stage programs in active trials; Focus on undruggable targets like EphA2; Partnerships with academic and pharma leaders; Technology based on Nobel Prize-winning science; Headquartered in Cambridge, UK with US operations in Cambridge, MA
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