A-Alpha Bio measures and predicts protein-protein interactions using synthetic biology and machine learning. AlphaSeq enables high-throughput measurement of millions of binding affinities. AlphaBind uses a global database to predict binding strength from protein sequence. The company partners with major pharmaceutical firms and academic institutions to advance drug discovery.
Predict antibody-antigen binding affinities for therapeutic development; Identify degradable neo-substrates for targeted cancer therapies; Engineer protein interfaces for novel immunocytokines; Validate computational protein designs through experimental measurement; Accelerate discovery of molecular glues for oncology applications
Measured over a billion protein-protein interactions to date; Partners with Biogen, Gilead, Amgen, and Google; Founded at University of Washington's Institute for Protein Design